Scientific Positions

2-year postdoc position - part of Innovative Medicines Initiative: "IMPRiND" 899353

Jensen Group - Neurodegenerative Disease Laboratory at DANDRITE (The Danish Research Institute of Translational Neuroscience, see dandrite.au.dk), wants to fill vacant position.

The postdoctoral position is a full-time position with 37 hours per week. Preferential starting date is from June 2017. The main goal of the project is: ”Modelling effects of Parkinson-associated alpha-synuclein aggregates on cellular calcium homeostasis”.

DANDRITE is the Danish node of the Nordic EMBL Partnership for Molecular Medicine. DANDRITE was established by Lundbeckfonden and Aarhus University in 2013 and performs basic and translational research in brain and the nervous system. DANDRITE is an interdisciplinary research centre affiliated with two faculties at Aarhus University, the Faculty of Health and the Faculty of Science and Technology. The centre has ties to Aarhus University Hospital.

The workplace address is Aarhus University, Ole Worms Allé 3, Bldg. 1171, 8000 Aarhus C.

Job responsibilities
The applicant will perform cell biological experiments in cell lines and isolated neurons and conduct fluorescence based cytosolic calcium measurements. As calcium sensors will be used Fura2 and viral based genetic calcium sensors. Moreover, the applicant will identify optimal genetic calcium sensors and generate neurons specific expression vectors for their use in primary brain cell cultures. The Jensen Group has recently made several progress to understand the role of intracellular alpha-synuclein aggregates effects on cellular calcium homeostasis. This project aim as part of the IMPRIND consortium to develop this insight into cell based assays that will allow comparative studies between different alpha-synuclein aggregate strains and to conduct mechanistic studies on selected targets.

Specific competences
The ideal candidate has experience in live cell  microscopy, cellular calcium imaging and viral vector based gene expression.

Furthermore the candidate is expected to be able to manage projects, interact with international collaborators, develop novel technical approaches, conduct firm, kind and thorough supervision and be a good team player.

We offer
• An exciting collaborative international research environment at DANDRITE and the larger NeuroCampus Aarhus of Aarhus University.

• A challenging position in an exciting new project addressing important fundamental question on the impact of intracellular protein aggregation on neuron structure/function addressed with novel technical approaches.

The project is carried out in a highly collaborative team at the Neurodegenerative disease laboratory and will be conducted as part of the multi-lab academic/pharma collaborative IMPRiND project funded by IMI (about IMI see: http://www.imi.europa.eu/). It will thus allow further development of project management, collaboration, experimental techniques, and data dissemination skills.

For further information about the position: prospective candidates are encouraged to contact Professor Poul Henning Jensen, e-mail: phj@biomed.au.dk (please note that applications cannot be sent to this e-mail address - see section on ‘Application’ below) before deciding on submitting an application.

Required qualifications
This position requires a PhD degree in neuroscience or related fields.
Please also see section about 'Specific competences' above.

Required qualifications

Appointment as a postdoc requires academic qualifications at PhD level.

Formalities and references

 

  • Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
  • The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
  • Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
  • Further information on qualification requirements and job description can be found in the Memorandum on Job Structure for Academic Staff at Danish Universities (in Danish).

     

    Application

    Applications must be accompanied by a CV, diploma, a list of publications, a research plan as well as a teaching portfolio. A maximum of ten of the publications of greatest relevance to the job must be submitted. If you have an assessment within the same job title (completed after March 1, 2016 at AU, Health), then this can be attached to the application.

    Further information on the application and supplementary materials may be found in the faculty's Guidelines for applicants and Aarhus University's Guidelines on the use of teaching portfolios.

    The assessment committee may decide to include non-submitted material in its assessment. In such cases, the applicant will be informed and obliged to submit material, unless the application is withdrawn.

    Applications submitted through channels other than the online application form below or applications which are not received by the application deadline will not be considered.

    All interested candidates are encouraged to apply, regardless of their personal background.

  • Deadline

    All applications must be made online and received by:

    30.04.2017
    Please apply online here

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