Videnskabelige stillinger

2-year postdoctoral position within molecular biology and immunology 950966

Aarhus University, Faculty of Health, Department of Clinical Medicine, Department of Infectious Diseases wants to fill a vacant position as postdoc.

The position, which is a full-time position with 37 hours per week, is expected to be filled on 1 February 2018 or as soon as possible thereafter. The position is a fixed-term employment of two years with effect from the starting date of employment. There is the possibility of extension of the employment period, if the project secures additional funding. You will be employed with reference to professor Peter Nejsum

The workplace address is Palle Juul-Jensens Boulevard 99, 8200 Aarhus N.

Project summary and job description

The main focus of this position is to explore the role of parasite derived extracellular vesicles and their role in host-parasite interaction. The project is supervised by Professor Peter Nejsum and is part of the project “Intercepting worm communication” (2016-20) funded by The Danish Council for Independent Research and includes national and international collaborator.

Parasitic worms have turned into true masters of host manipulation, as they can dampen inflammation to optimize their own survival in tissues, but very little is known about the specific mechanisms by which they do so. Excretory-secretory antigens from parasitic worms are important in this context but a few recent studies have indicated that parasite extracellular vesicles (EVs) are crucial for host-parasite communication. Deciphering of this communication opens up for a new fundamental understanding of host-parasite interaction and thereby paves the way for novel treatments, new drug targets and vaccines.

The aim of the project is to provide fundamental and novel insight into how parasites manipulate an aggressive immune system in order survive within their host. To do so the role of EVs in host-parasite  communication will be investigated using in vitro and in vivo studies. EVs from parasitic worms will be isolated, identified and characterized. Their content will be analysed using proteomics and next generation sequencing. In vitro and in vivo studies in lab animals will be conducted to functional test the role of EVs in the host-parasite interaction with focus on immunological aspects.

The position will also include supervision of students (or involvement in other projects), applying for funding, publication of articles and may include some teaching.

I am therefore looking for highly skilled candidate with a strong personal drive that are eager to learn, ready to push own limits, have a positive attitude, being a team player and have a strong desire to make fundamental discoveries within science.
International travel to, and stays at collaborating laboratories may be required.

Key criteria for the assessment of candidates
The candidate should have:
• PhD degree in the fields of molecular biology, biotechnology, immunology or other related fields.
• Published peer-reviewed articles in international recognized journals
• Fluency in written and spoken English

Qualification requirements
Applicants with the following professional and personal qualifications will be highly advantaged:
• Experience with extracellular vesicles (e.g. isolation and characterization)
• Experience with ELISA, WB, Flow cytometry and other relevant immunological methods
• Experience with cell cultures and mouse models
• Experience with bioinformatics (proteomics and/or small RNA analysis)
• Good biological insight
• Post-doctoral experience
• Rich in initiative and a strong motivation for research
• Good supervisor and communication skills
• Well-developed collaborative skills and a team player

We offer
• A challenging position in an exciting and emerging research area
• A supporting team and good working environment
• Good opportunities to expand your network with world-leading scientists
• Opportunity to development your scientific skills, managing projects, disseminate and publish your research.

For further information about the position, please contact Peter Nejsum by phone: +45 50541392

Kvalifikationskrav

Ansættelse som post doc forudsætter videnskabelige kvalifikationer på ph.d.-niveau.

Formalia og henvisninger

  • Vedrørende ansættelsesproceduren henvises til ministeriets Bekendtgørelse om ansættelse af videnskabeligt personale ved universiteter.
  • Ansættelse sker i henhold til Akademikerne.
  • Aflønning sker i overensstemmelse med ovenstående og Lønkatalog for medarbejdere ved Health.
  • Vedrørende kvalifikationskrav og stillingsindhold henvises til stillingsstruktur for videnskabeligt personale ved universiteter.

    Ansøgning

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    Vedrørende ansøgning og bilag hertil henvises til fakultetets Vejledning for ansøgere samt AU’s Vejledning til anvendelse af undervisningsportfolio.

    Bedømmelsesudvalget kan beslutte at inddrage ikke indsendt materiale i forbindelse med udvalgsarbejdet. Ansøgeren vil i givet fald blive underrettet herom og da være forpligtet til at indsende materiale, medmindre ansøgningen trækkes tilbage.

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  • Ansøgningsfrist

    Alle ansøgninger skal være lavet online og modtaget senest:

    21.12.2017
    Søg stilling online her

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