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Heidi Kaastrup Müller

Title

Associate Professor

Primary affiliation

Heidi Kaastrup Müller

Areas of expertise

  • Regulation and function of sortilin
  • Proteolytic processing of APP
  • Mechanisms of p75NTR signaling
  • Mechanism of Ketamine

Contact information

Telephone number
Email address

Research

Our research focuses on understanding the molecular mechanisms controlling proteolytic processing of amyloid precursor protein, p75NTR and sortilin in neurodegenerative and neuropsychiatric disorders and evaluating potential approaches to target these processes for therapeutic purposes. We are particularly interested in regulatory mechanisms mediated by protein-protein interactions.

A second topic of research interest is molecular mechanisms contributing to fast-acting antidepressant effects of ketamine and psychedelics. Studies include receptor signaling, trafficking, and protein-protein interactions.

Teaching activities

I currently teach the course Neurobiology under the Master's degree Programme in Molecular Medicine, and the course Biological Psychiatry under the Master's degree Programme in Medicine. I supervise Master’s and PhD students within the areas of molecular biology and neuroscience. 

Selected publications

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