As a postdoc at the Department of Biomedicine, I conduct research on tumor-infiltrating T cells, cancer metabolism and metabolic reprogramming. In my work, I am particularly interested in ex vivo expansion and reprogramming of primary tumor-infiltrating T cells.
I have a degree in Molecular Medicine and a background in cancer immunology, immunotherapy and epigenetics.
I conduct research in tumor-infiltrating T cells from lung cancer patients with particular focus on exhausted T cells. Using newly established laboratory TIL expansion protocols together with lipid-nanoparticles and CRISPR interference, I aim to reprogram exhausted T cells to become effective tumor-killing T cells. My research will contribute to the improvement and increased applicability of T cell therapy in the future.
I collaborate with the Department of Cardiothoracic and Vascular Surgery, the Department of Pathology and the Department of Clinical Biochemistry at Aarhus University Hospital in collecting patient-derived materiel for our lung cancer biobank.
I cooperate with the Department of Molecular Medicine at Aarhus University on single-cell RNA sequencing analysis of T cells.
I primarily manage our research project within exploration of exhausted T cells in lung cancer. I am responsible for developing and optimizing new laboratory protocols and assays, including new spectral flowcytometry panels and single-cell RNA sequencing analyses. Alongside my research activities, I also supervise students.
