80 PURE

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Moldovan, L.-I., Hansen, T. B., Venø, M. T., Okholm, T. L. H., Andersen, T. L., Hager, H., Iversen, L., Kjems, J., Johansen, C. & Kristensen, L. S. (2019). High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome. BMC Medical Genomics, 12(1), Artikel 174. https://doi.org/10.1186/s12920-019-0616-2

Li, A., Geyer, F. C., Blecua, P., Lee, J. Y., Selenica, P., Brown, D. N., Pareja, F., Lee, S. S. K., Kumar, R., Rivera, B., Bi, R., Piscuoglio, S., Wen, H. Y., Lozada, J. R., Gularte-Mérida, R., Cavallone, L., Rezoug, Z., Nguyen-Dumont, T., Peterlongo, P. ... KConFab Investigators (2019). Homologous recombination DNA repair defects in PALB2-associated breast cancers. npj Breast Cancer, 5(1), Artikel 23. https://doi.org/10.1038/s41523-019-0115-9

Andersen, N. S. B., Larsen, S. M., Nissen, S. K., Jørgensen, S. E., Mardahl, M., Christiansen, M., Kay, L. & Mogensen, T. H. (2019). Host genetics, innate immune responses, and cellular death pathways in poliomyelitis patients. Frontiers in Microbiology, 10, Artikel 1495. https://doi.org/10.3389/fmicb.2019.01495

Madsen, P., Isaksen, T. J., Siupka, P., Tóth, A. E., Nyegaard, M., Gustafsen, C. & Nielsen, M. S. (2019). HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA. Scientific Reports, 9, Artikel 611. https://doi.org/10.1038/s41598-018-37336-6

Hensel, N., Raker, V., Förthmann, B., Detering, N. T., Kubinski, S., Buch, A., Katzilieris-Petras, G., Spanier, J., Gudi, V., Wagenknecht, S., Kopfnagel, V., Werfel, T. A., Stangel, M., Beineke, A., Kalinke, U., Paludan, S. R., Sodeik, B. & Claus, P. (2019). HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0. Journal of Neuroinflammation, 16(1), Artikel 248. https://doi.org/10.1186/s12974-019-1647-5

Gomez-Ospina, N., Scharenberg, S. G., Mostrel, N., Bak, R. O., Mantri, S., Quadros, R. M., Gurumurthy, C. B., Lee, C., Bao, G., Suarez, C. J., Khan, S., Sawamoto, K., Tomatsu, S., Raj, N., Attardi, L. D., Aurelian, L. & Porteus, M. H. (2019). Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I. Nature Communications, 10(1), 4045. Artikel 4045. https://doi.org/10.1038/s41467-019-11962-8

Lafaille, F. G., Harschnitz, O., Lee, Y. S., Zhang, P., Hasek, M. L., Kerner, G., Itan, Y., Ewaleifoh, O., Rapaport, F., Carlile, T. M., Carter-Timofte, M. E., Paquet, D., Dobbs, K., Zimmer, B., Gao, D., Rojas-Duran, M. F., Kwart, D., Rattina, V., Ciancanelli, M. J. ... Zhang, S. Y. (2019). Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. Nature Medicine, 25(12), 1873-1884. https://doi.org/10.1038/s41591-019-0672-3

Fragniere, A. M. C., Stott, S. R. W., Fazal, S. V., Andreasen, M., Scott, K. & Barker, R. A. (2019). Hyperosmotic stress induces cell-dependent aggregation of α-synuclein. Scientific Reports, 9, Artikel 2288. https://doi.org/10.1038/s41598-018-38296-7

Dall Jensen, R., Ravn, S. & Christensen, M. K. (2019). Identification and development of talent in surgery: A scoping study across the performance domains of surgery, sport, and music. European Journal of Training and Development, 43(3/4), 272-305. https://doi.org/10.1108/EJTD-07-2018-0070

Walther, R., Winther, A., Fruergaard, A. S., Akker, W. V. D., Sørensen, L., Nielsen, S. M., Olesen, M. T. J., Dai, Y., Jeppesen, H. S., Lamagni, P., Savateev, A., Pedersen, S. L., Frich, C. K., Vigier, C. A., Lock, N., Singh, M., Bansal, V., Meyer, R. L. & Zelikin, A. N. (2019). Identification and Directed Development of Non‐Organic Catalysts with Apparent Pan‐Enzymatic Mimicry into Nanozymes for Efficient Prodrug Conversion. Angewandte Chemie International Edition, 58(1), 278-282. https://doi.org/10.1002/anie.201812668

Liou, A. Y., Molday, L. L., Wang, J., Andersen, J. P. & Molday, R. S. (2019). Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. Journal of Biological Chemistry, 294(17), 6809-6821. https://doi.org/10.1074/jbc.RA118.007270

de Groot, T., Ebert, L. K., Christensen, B. M., Andralojc, K., Cheval, L., Doucet, A., Mao, C., Baumgarten, R., Low, B. E., Sandhoff, R., Wiles, M. V., Deen, P. M. T. & Korstanje, R. (2019). Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice. Journal of the American Society of Nephrology : JASN, 30(12), 2322-2336. https://doi.org/10.1681/ASN.2018050549

Thomsen, M. M., Jørgensen, S. E., Storgaard, M., Kristensen, L. S., Gjedsted, J., Christiansen, M., Gad, H. H., Hartmann, R. & Mogensen, T. H. (2019). Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza. European Journal of Immunology, 49(11), 2111-2114. https://doi.org/10.1002/eji.201848083

Rinschen, M. M., Ivanisevic, J., Giera, M. & Siuzdak, G. (2019). Identification of bioactive metabolites using activity metabolomics. Nature Reviews Molecular Cell Biology, 20(6), 353-367. https://doi.org/10.1038/s41580-019-0108-4

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., Awashti, S., Belliveau, R., Bettella, F., Buxbaum, J. D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Christensen, J. H. ... Børglum, A. D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51(3), 431-444. https://doi.org/10.1038/s41588-019-0344-8

Kilian, M. & Tettelin, H. (2019). Identification of Virulence-Associated Properties by Comparative Genome Analysis of Streptococcus pneumoniae, S. pseudopneumoniae, S. mitis, Three S. oralis Subspecies, and S. infantis. mBio, 10(5), Artikel e01985-19. https://doi.org/10.1128/mBio.01985-19

Hotter, D., Bosso, M., Jønsson, K. L., Krapp, C., Stürzel, C. M., Das, A., Littwitz-Salomon, E., Berkhout, B., Russ, A., Wittmann, S., Gramberg, T., Zheng, Y., Martins, L. J., Planelles, V., Jakobsen, M. R., Hahn, B. H., Dittmer, U., Sauter, D. & Kirchhoff, F. (2019). IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation. Cell Host & Microbe, 25(6), 858-872.e13. https://doi.org/10.1016/j.chom.2019.05.002

Kragstrup, T. W., Adams, M., Lomholt, S., Nielsen, M. A., Heftdal, L. D., Schafer, P. & Deleuran, B. (2019). IL-12/IL-23p40 identified as a downstream target of apremilast in ex vivo models of arthritis. Therapeutic Advances in Musculoskeletal Disease, 11. https://doi.org/10.1177/1759720X19828669

Charlton, J. R., Harer, M. W., Swan, C. & Nielsen, R. (2019). Immature megalin expression in the preterm neonatal kidney is associated with urinary loss of vitamin carrier proteins. Pediatric Research, 85(3), 405-411. https://doi.org/10.1038/s41390-018-0261-z

Møller, A. B., Vendelbo, M. H., Schjerling, P., Couppé, C., Møller, N., Kjær, M., Hansen, M. & Jessen, N. (2019). Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle. Frontiers in Physiology, 10, Artikel 736. https://doi.org/10.3389/fphys.2019.00736

Tansey, M. G. & Romero-Ramos, M. (2019). Immune system responses in Parkinson's Disease: early and dynamic. The European journal of neuroscience, 49(3), 364-383. https://doi.org/10.1111/ejn.14290

Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, M., Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, T., Rasmussen, S. & Thompson, W. K. (2019). Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders. European Journal of Human Genetics, 27(9), 1445-1455. https://doi.org/10.1038/s41431-019-0402-9

Su, J., Hughes, A. D., Simonsen, U., Nielsen-Kudsk, J. E., Parker, K. H., Howard, L. S. & Mellemkjaer, S. (2019). Impact of Pulmonary Endarterectomy on Pulmonary Arterial Wave Propagation and Reservoir Function. American Journal of Physiology: Heart and Circulatory Physiology, 317(3), H505-H516. https://doi.org/10.1152/ajpheart.00181.2019

Sembach, F. E., Fink, L. N., Johansen, T., Boland, B. B., Secher, T., Thrane, S. T., Nielsen, J. C., Fosgerau, K., Vrang, N., Jelsing, J., Pedersen, T. X. & Ostergaard, M. V. (2019). Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice. Physiological Reports, 7(24), Artikel 14333. https://doi.org/10.14814/phy2.14333

Mardahl, M., Jørgensen, S. E., Schneider, A., Raaschou-Jensen, K., Holm, M., Veirum, J., Kristensen, T. K., Johansen, I. S., Christiansen, M., Assing, K. & Mogensen, T. H. (2019). Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC. British Journal of Haematology, 186(3), 471-476. https://doi.org/10.1111/bjh.15947

Rasmussen, C. B., Christiansen, G., Vad, B. S., Lynggaard, C., Enghild, J. J., Andreasen, M. & Otzen, D. (2019). Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation. Protein Science, 28(3), 633-642. https://doi.org/10.1002/pro.3566

Jensen, T. B., Bartels, D., Sædder, E. A., Poulsen, B. K., Andersen, S. E., Christensen, M. M. H., Nielsen, L. & Christensen, H. R. (2019). Implementation of TNF-biosimilars (Infliximab and Eternacept) in Danish departments of rheumatology. Annals of the Rheumatic Diseases, 78(Suppl. 2), 237-237. Artikel OP0310. https://doi.org/10.1136/annrheumdis-2019-eular.1383

Moosa, S., Gregersen, P. A., Hald, J. D. & Vogel, I. (2019). Implications of identifying a PLS3 deletion as an incidental finding on prenatal testing. Poster-session præsenteret på The 14th biannual International Skeletal Dysplasia Society Meeting , Oslo.

Hagensen, M. K., Mortensen, M. B., Kjolby, M., Palmfeldt, J., Bentzon, J. F. & Gregersen, S. (2019). Increased retention of LDL from type 1 diabetic patients in atherosclerosis-prone areas of the murine arterial wall. Atherosclerosis, 286, 156-162. https://doi.org/10.1016/j.atherosclerosis.2019.02.027

El-Akkawi, A. I., de Paoli, F. V., Bendixen, M. & Christensen, T. D. (2019). Indication and timing of surgery are essential in stabilization of the chest wall in flail chest trauma patients. Abstract fra 29th Annual Meeting SSRCTS, Geilo, Norge.

Skovdal, S. M., Christiansen, S. H., Johansen, K. S., Viborg, O., Bruun, N. H., Jensen-Fangel, S., Holm, I. E., Vorup-Jensen, T. & Petersen, E. (2019). Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs. PLoS One, 14(10), Artikel e0223647. https://doi.org/10.1371/journal.pone.0223647

Yanagi, Y., Abdullah Al Masud, H. M., Watanabe, T., Sato, Y., Goshima, F., Kimura, H. & Murata, T. (2019). Initial characterization of the Epstein–Barr virus BSRF1 gene product. Viruses, 11(3), Artikel 285. https://doi.org/10.3390/v11030285

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10, Artikel 2548. https://doi.org/10.1038/s41467-019-10461-0

Nandakumar, R., Windross, S. J. & Paludan, S. R. (2019). Intercellular communication in the innate immune system through the cGAS-STING pathway. I J. Sohn (red.), DNA Sensors and Inflammasomes (s. 1-11). Elsevier. https://doi.org/10.1016/bs.mie.2019.07.007

Kaleviste, E., Saare, M., Leahy, T. R., Bondet, V., Duffy, D., Mogensen, T. H., Jørgensen, S. E., Nurm, H., Ip, W., Davies, E. G., Sauer, S., Syvänen, A. C., Milani, L., Peterson, P. & Kisand, K. (2019). Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined. European Journal of Immunology, 49(5), 790-800. https://doi.org/10.1002/eji.201847955

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M. ... Koenen, K. C. (2019). International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications, 10(1), Artikel 4558. https://doi.org/10.1038/s41467-019-12576-w

Wittenborn, T. R., Hagert, C. & Degn, S. E. (2019). Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity. Journal of visualized experiments : JoVE, 2019(146), Artikel e59397. https://doi.org/10.3791/59397

Nandakumar, R., Tschismarov, R., Meissner, F., Prabakaran, T., Krissanaprasit, A., Farahani, E., Zhang, B. C., Assil, S., Martin, A., Bertrams, W., Holm, C. K., Ablasser, A., Klause, T., Thomsen, M. K., Schmeck, B., Howard, K. A., Henry, T., Gothelf, K. V., Decker, T. & Paludan, S. R. (2019). Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling. Nature Microbiology, 4, 701-713. https://doi.org/10.1038/s41564-019-0367-z

Kaspersen, A. E., Hasenkam, J. M., Leipziger, J. G. & Djurhuus, J. C. (2019). Introduktion til at skrive et videnskabeligt abstract. Ugeskrift for Læger, 181(21), Artikel V02190103. http://ugeskriftet.dk/videnskab/introduktion-til-skrive-et-videnskabeligt-abstract

Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019). Investigating the association between body fat and depression via Mendelian randomization. Translational Psychiatry, 9(1), Artikel 184. https://doi.org/10.1038/s41398-019-0516-4

Speed, D., Hemani, G., Speed, M. S., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Børglum, A. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica, 139(4), 395-397. https://doi.org/10.1111/acps.13009

Weingart, O. G., Eyer, K., Lüchtenborg, C., Sachsenheimer, T., Brügger, B., Van Oostrum, M., Wollscheid, B., Dittrich, P. S. & Loessner, M. J. (2019). In vitro quantification of botulinum neurotoxin type A1 using immobilized nerve cell-mimicking nanoreactors in a microfluidic platform. Analyst, 144(19), 5755-5765. https://doi.org/10.1039/c9an00817a

Staehr, C., Rajanathan, R. & Matchkov, V. V. (2019). Involvement of the Na ⁺ ,K ⁺-ATPase isoforms in control of cerebral perfusion. Experimental Physiology, 104(7), 1023-1028. https://doi.org/10.1113/EP087519

Mogensen, T. H. (2019). IRF and STAT transcription factors - From basic biology to roles in infection, protective immunity, and primary immunodeficiencies. Frontiers in Immunology, 9, Artikel 3047. https://doi.org/10.3389/fimmu.2018.03047

Alstrup, T., Eijken, M., Bohn, A. B., Møller, B. & Damsgaard, T. E. (2019). Isolation of Adipose Tissue-Derived Stem Cells: Enzymatic Digestion in Combination with Mechanical Distortion to Increase Adipose Tissue-Derived Stem Cell Yield from Human Aspirated Fat. Current Protocols in Stem Cell Biology, 48(1), Artikel e68. https://doi.org/10.1002/cpsc.68

Poulsen, S. B. & Fenton, R. A. (2019). K+ and the renin-angiotensin-aldosterone system: new insights into their role in blood pressure control and hypertension treatment. The Journal of Physiology, 597(17), 4451-4464. https://doi.org/10.1113/JP276844

Fredslund, S. O., Gravholt, C. H., Laursen, B. E. & Jensen, A. B. (2019). Key metabolic parameters change significantly in early breast cancer survivors: An explorative PILOT study. Journal of Translational Medicine, 17(1), Artikel 105. https://doi.org/10.1186/s12967-019-1850-2

Laursen, B. E. & Simonsen, U. (2019). Kolinoceptoraktiverende og -blokerende lægemidler. I K. Brøsen, U. Simonsen & K. Dalhoff (red.), Basal og klinisk farmakologi (6. udg., s. 146-162). FADL's Forlag.

Simonsen, U. & Rosenkilde, M. (2019). Kvantitativ beskrivelse af lægemiddel-receptor-interaktion. I K. Brøsen, U. Simonsen & K. DalHoff (red.), Basal og klinisk farmakologi (6. udg., s. 49-64). FADL's Forlag.

King, D., Glynn, M. D., Cindric, S., Kernan, D., O’Connell, T., Hakimjavadi, R., Kearney, S., Ackermann, T., Berbel, X. M., Llobera, A., Simonsen, U., Laursen, B. E., Redmond, E. M., Cahill, P. A. & Ducrée, J. (2019). Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform. Scientific Reports, 9, Artikel 4157. https://doi.org/10.1038/s41598-019-40612-8

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