Gormsen, L. C., Søndergaard, E., Christensen, N. L., Jakobsen, S., Nielsen, E. H. T., Munk, O. L., Tolbod, L. P., Jessen, N. & Nielsen, S. (2018).
Metformin does not Affect Postabsorptive Hepatic Free Fatty Acid Uptake, Oxidation or Resecretion in Humans: A 3-months Placebo Controlled Clinical Trial in Patients with Type 2 Diabetes and Healthy Controls.
Diabetes, Obesity and Metabolism,
20(6), 1435-1444.
https://doi.org/10.1111/dom.13244
Hunter, R. W., Hughey, C. C., Lantier, L.
, Sundelin, E. I., Peggie, M., Zeqiraj, E., Sicheri, F.
, Jessen, N., Wasserman, D. H. & Sakamoto, K. (2018).
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.
Nature Medicine,
24(9), 1395-1406.
https://doi.org/10.1038/s41591-018-0159-7
Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, J. B.
, Pedersen, S. B., Richelsen, B. & Jessen, N. (2018).
Metformin Targets Brown Adipose Tissue in vivo and Reduces Oxygen Consumption in vitro.
Diabetes, Obesity and Metabolism,
20(9), 2264-2273.
https://doi.org/10.1111/dom.13362
Jensen, N., Schrøder, H. D., Kildall Hejbøl, E.
, Thomsen, J. S., Brüel, A., Larsen, F., Vinding, M. C., Orlowski, D., Füchtbauer, E.-M., Oliveira, J. R. M.
& Pedersen, L. (2018).
Mice knocked out for the primary brain calcification - associated gene Slc20a2 show unimpaired pre-natal survival but retarded growth and nodules in the brain that grow and calcify over time.
American Journal of Pathology,
188(8), 1865-1881.
https://doi.org/10.1016/j.ajpath.2018.04.010
Lisboa, S. F., Issy, A. C., Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimarães, F. S., Cunha, F. Q., Verri, W. A.
& Joca, S. R. L. (2018).
Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms.
Journal of Neuroimmunology,
314, 58-66.
https://doi.org/10.1016/j.jneuroim.2017.11.008
Kopp, S., Krüger, M., Bauer, J., Wehland, M.
, Corydon, T. J., Sahana, J., Nassef, M. Z., Melnik, D., Bauer, T. J., Schulz, H., Schütte, A., Schmitz, B., Oltmann, H., Feldmann, S., Infanger, M.
& Grimm, D. (2018).
Microgravity Affects Thyroid Cancer Cells during the TEXUS-53 Mission Stronger than Hypergravity.
International Journal of Molecular Sciences ,
19(12), Artikel 4001.
https://doi.org/10.3390/ijms19124001
Lindman, J.
, Khammy, M. M., Lundegaard, P. R.
, Aalkjr, C. & Jepps, T. A. (2018).
Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle.
Hypertension,
71(2), 336-345.
https://doi.org/10.1161/HYPERTENSIONAHA.117.10152
Staehr, C., Rajanathan, R., Bouzinova, E., Aalkjær, C., Bach, F. W. & Matchkov, V. (2018).
Migraine associated mutation in the α2 isoform Na+,K+-ATPase leads to disturbance in neurovascular coupling.
Proceedings of the Physiological Society,
41(SA066).
Andersen, G. B., Knudsen, A., Hager, H., Hansen, L. L. & Tost, J. (2018).
miRNA profiling identifies deregulated miRNAs associated with osteosarcoma development and time to metastasis in two large cohorts.
Molecular Oncology,
12(1), 114-131.
https://doi.org/10.1002/1878-0261.12154
Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M. M., Thiel, S. & Andersen, G. R. (2018).
Models of the complement C1 complex.
Proceedings of the National Academy of Sciences (PNAS),
115(17), E3866. Artikel E3866.
https://doi.org/10.1073/pnas.1803577115
Zhang, J., Cong, J., Yang, J.
, Thomsen, J. S., Andreasen, A., Chang, S.-J., Wang, K.-Y., Gu, L. & Zhai, X.-Y. (2018).
Morphologic and morphometric study on microvasculature of developing mouse kidneys.
American Journal of Physiology: Renal Physiology,
315(4), F852-F860.
https://doi.org/10.1152/ajprenal.00615.2017
Nielsen, C. S.-Z., Væggemose, M., Jacobsen, A. B., Fuglsang-Frederiksen, A., Andersen, H., Harbo, T. & Tankisi, H. (2018).
Motor Unit Number Estimation Methods for quantification of motor unit loss in Guillain Barre Syndrome.
Clinical Neurophysiology,
129(Supplement 1), e80. Artikel F37.
https://doi.org/10.1016/j.clinph.2018.04.200
O'Sullivan, A., Lindsay, T.
, Prudnikova, A., Erdi, B., Dickinson, M.
& von Philipsborn, A. C. (2018).
Multifunctional Wing Motor Control of Song and Flight.
Current Biology,
28(17), 2705-2717.e4.
https://doi.org/10.1016/j.cub.2018.06.038
Nissen, S. K., Pedersen, J. G., Helleberg, M.
, Kjaer, K., Thavachelvam, K., Obel, N.
, Tolstrup, M., Jakobsen, M. R. & Mogensen, T. H. (2018).
Multiple Homozygous Variants in the STING-Encoding TMEM173 Gene in HIV Long-Term Nonprogressors.
Journal of Immunology,
200(10), 3372-3382.
https://doi.org/10.4049/jimmunol.1701284
Frølunde, A. S., Ohlenbusch, M. E., Berg-Hansen, K., Jessen, N., Kim, S. & Boedtkjer, E. (2018).
Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction.
Breast Cancer Research,
20(1), Artikel 20.
https://doi.org/10.1186/s13058-018-0952-8
Kumar, N. A.
, van der Sluis, R. M., Mota, T., Pascoe, R., Evans, V. A., Lewin, S. R. & Cameron, P. U. (2018).
Myeloid Dendritic Cells Induce HIV Latency in Proliferating CD4+ T Cells.
Journal of Immunology,
201(5), 1468-1477.
https://doi.org/10.4049/jimmunol.1701233
Wang, J., Sieljacks, P., Grønnebæk, T. S., Jakobsgaard, J. E., Rindom, E., Gravholdt, A.
, Herskind, J. H., Møller, A. B., Musci, R.
, Bøtker, H. E., Hamilton, K., Miller, B.
, de Paoli, F. V. & Vissing, K. (2018).
Myofibrillar Response to Low-load Blood-flow Restricted Exercise versus Heavy Resistance Exercise. Poster-session præsenteret på ACSM Conference on Integrative Physiology of Exercise, San Diego, USA.
Lee, S., Axelsen, T. V., Jessen, N., Pedersen, S. F.
, Vahl, P. & Boedtkjer, E. (2018).
Na+ ,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice.
Oncogene,
37(41), 5569-5584.
https://doi.org/10.1038/s41388-018-0353-6
Lou, S., Petersen, O. B., Jørgensen, F. S.
, Lund, I. C. B., Kjærgaard, S.
, Vogel, I., Fagerberg, C., Svaneby, D., Bache, I., Hansen, J. F. & Danish Cytogenetic Central Registry Study Group (2018).
National screening guidelines and developments in prenatal diagnoses and live births of Down syndrome in 1973–2016 in Denmark.
Acta Obstetricia et Gynecologica Scandinavica,
97(2), 195-203.
https://doi.org/10.1111/aogs.13273
Papp, V., Illés, Z., Magyari, M.
, Koch-Henriksen, N., Kant, M.
, Pfleger, C. C., Roemer, S. F., Jensen, M. B., Petersen, A., Nielsen, H. H., Rosendahl, L., Mezei, Z.
, Christensen, T., Svendsen, K. B., Jensen, P. E. H., Lydolph, M. C., Heegaard, N., Frederiksen, J. L., Sellebjerg, F.
... Petersen, T. (2018).
Nationwide prevalence and incidence study of neuromyelitis optica spectrum disorder in Denmark. Neurology,
91(24), E2265-E2275.
https://doi.org/10.1212/WNL.0000000000006645
Yan, X., Kononenko, N. L.
, Brüel, A., Thomsen, J. S. & Poy, M. N. (2018).
Neuronal Cell Adhesion Molecule 1 Regulates Leptin Sensitivity and Bone Mass.
Calcified Tissue International,
102(3), 329-336.
https://doi.org/10.1007/s00223-017-0361-5
B, L.-L.
, FM, D., OB, H., JR, H. & CJ, W. (2018).
Neutral lineage tracing of proliferative embryonic and adult mammary stem/progenitor cells. Development (Cambridge),
145(14), Artikel dev164079.
https://doi.org/10.1242/dev.164079
Ejerskov, C., Krogh, K., Børglum, A., Østergaard, J. R. & Haagerup, A. (2018).
NF1 and the gastrointestinal canal: A high prevalence of gastrointestinal symptoms correlated to constipation.. Poster-session præsenteret på 18th European Neurofibromatosis Meeting, Paris, Frankrig.
Hansen, A. L., Buchan, G. J., Rühl, M., Mukai, K., Salvatore, S. R., Ogawa, E.
, Andersen, S. D., Iversen, M. B., Thielke, A. L., Gunderstofte, C., Motwani, M.
, Møller, C. T., Jakobsen, A. S., Fitzgerald, K. A., Roos, J., Lin, R.
, Maier, T. J., Goldbach-Mansky, R., Miner, C. A.
... Holm, C. K. (2018).
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Proceedings of the National Academy of Sciences (PNAS),
115(33), E7768-E7775.
https://doi.org/10.1073/pnas.1806239115
Dunphy, G., Flannery, S. M., Almine, J. F., Connolly, D. J., Paulus, C.
, Jønsson, K. L., Jakobsen, M. R., Nevels, M. M., Bowie, A. G. & Unterholzner, L. (2018).
Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Molecular Cell,
71(5), 745-760.e5.
https://doi.org/10.1016/j.molcel.2018.07.034
Joshi, S., Kvistgaard, H., Kamperis, K., Færch, M., Hagstrøm, S., Gregersen, N., Rittig, S. & Christensen, J. H. (2018).
Novel and recurrent variants in AVPR2 in 19 families with X-linked congenital nephrogenic diabetes insipidus.
European Journal of Pediatrics,
177(9), 1399-1405.
https://doi.org/10.1007/s00431-018-3132-z
Graversen, L., Haagerup, A., Andersen, B. N., Petersen, K. K., Gjørup, V., Gudmundsdottir, G., Vogel, I. & Gregersen, P. A. (2018).
Novel TRPV4 variant causes a severe form of metatropic dysplasia.
Clinical Case Reports,
6(9), 1774-1778.
https://doi.org/10.1002/ccr3.1598
Olagnier, D., Brandtoft, A. M., Gunderstofte, C., Villadsen, N. L., Krapp, C., Thielke, A. L., Laustsen, A., Peri, S.
, Hansen, A. L., Bonefeld, L., Thyrsted, J., Bruun, V., Iversen, M. B., Lin, L., Artegoitia, V. M., Su, C., Yang, L., Lin, R., Balachandran, S.
... Holm, C. K. (2018).
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.
Nature Communications,
9(1), Artikel 3506.
https://doi.org/10.1038/s41467-018-05861-7
Santana-Codina, N., Roeth, A. A., Zhang, Y., Yang, A., Mashadova, O., Asara, J. M., Wang, X., Bronson, R. T., Lyssiotis, C. A., Ying, H. & Kimmelman, A. C. (2018).
Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis.
Nature Communications,
9(1), 4945.
https://doi.org/10.1038/s41467-018-07472-8
Madesen, C., Prahm, K. P.
, Pedersen, L. H., Nilsson, C., Dziegiel, M. H. & Hedegaard, M. (2018).
Opsætning af screeningsprogram i Danmark for føtal og neonatal alloimmun trombocytopeni.
Ugeskrift for Læger.
Brüggemann, H., Jensen, A., Nazipi, S., Aslan, H., Meyer, R. L., Poehlein, A., Brzuszkiewicz, E., Al-Zeer, M. A., Brinkmann, V. & Söderquist, B. (2018).
Pan-genome analysis of the genus Finegoldia identifies two distinct clades, strain-specific heterogeneity, and putative virulence factors.
Scientific Reports,
8(1), Artikel 266.
https://doi.org/10.1038/s41598-017-18661-8
Andersen, M. A., Christensen, K. V., Badolo, L., Smith, G. P., Jeggo, R.
, Jensen, P. H., Andersen, K. J. & Sotty, F. (2018).
Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation.
Neurobiology of Disease,
116, 13-27.
https://doi.org/10.1016/j.nbd.2018.04.011
Lützenberg, R., Solano, K.
, Buken, C., Sahana, J., Riwaldt, S., Kopp, S., Krüger, M., Schulz, H., Saar, K., Huebner, N., Hemmersbach, R., Bauer, J., Infanger, M.
, Grimm, D. & Wehland, M. (2018).
Pathway Analysis Hints Towards Beneficial Effects of Long-Term Vibration on Human Chondrocytes.
Cellular Physiology and Biochemistry,
47(4), 1729-1741.
https://doi.org/10.1159/000491006
Milling, R. V., Grimm, D., Krüger, M., Grosse, J.
, Kopp, S., Bauer, J., Infanger, M. & Wehland, M. (2018).
Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension.
International Journal of Molecular Sciences ,
19(10), Artikel 3258.
https://doi.org/10.3390/ijms19103258
Andersen, M. A., Wegener, K. M.
, Larsen, S., Badolo, L., Smith, G. P., Jeggo, R.
, Jensen, P. H., Sotty, F., Christensen, K. V. & Thougaard, A. (2018).
PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats.
Toxicology,
395, 15-22.
https://doi.org/10.1016/j.tox.2018.01.003
von Mässenhausen, A., Tonnus, W., Himmerkus, N., Parmentier, S., Saleh, D., Rodriguez, D., Ousingsawat, J., Ang, R. L., Weinberg, J. M., Sanz, A. B., Ortiz, A., Zierleyn, A., Becker, J. U., Baratte, B., Desban, N., Bach, S.
, Schiessl, I. M., Nogusa, S., Balachandran, S. ... Linkermann, A. (2018).
Phenytoin inhibits necroptosis.
Cell Death & Disease,
9(3), 359. Artikel 359.
https://doi.org/10.1038/s41419-018-0394-3
Dayie, N. T. K. D., Tetteh-Ocloo, G., Labi, A. K., Olayemi, E.
, Slotved, H. C., Lartey, M. & Donkor, E. S. (2018).
Pneumococcal carriage among sickle cell disease patients in Accra, Ghana: Risk factors, serotypes and antibiotic resistance.
PLoS One,
13(11), Artikel e0206728.
https://doi.org/10.1371/journal.pone.0206728