80 PURE

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Publikationsliste

Ezran, C., Liu, S., Chang, S., Ming, J., Guethlein, L. A., Wang, M. F. Z., Dehghannasiri, R., Olivieri, J., Frank, H. K., Tarashansky, A., Koh, W., Jing, Q., Botvinnik, O., Antony, J., Pisco, A. O., Karkanias, J., Yang, C., Ferrell, J. E., Boyd, S. D. ... Tabula Microcebus Consortium (2025). Mouse lemur cell atlas informs primate genes, physiology and disease. Nature, 644(8075), 185-196. https://doi.org/10.1038/s41586-025-09114-8

Ahlqvist, V. H., Sjöqvist, H., Sjölander, A., Berglind, D., Lambert, P. C., Lee, B. K. & Madley-Dowd, P. (2025). Moving beyond risk ratios in sibling analysis: estimating clinically useful measures from family-based analysis. (s. 2025.05.16.25327702). medRxiv. https://doi.org/10.1101/2025.05.16.25327702

Vaeggemose, M., Kristensen, MH., Redda, M., Hansen, ES. S., Rodgers, O., Collier, GJ., Norquay, G., Wild, JM., Laustsen, C. & Schulte, RF. (2025). MR Spectroscopic Imaging of Hyperpolarized 129-Xenon in the Dissolved-Phase to Determine Regional Chemical Shifts of Hyperoxia in Healthy Porcine Lungs. NMR in Biomedicine, 38(6), Artikel e70063. https://doi.org/10.1002/nbm.70063

Rovsing, A. B., Green, K., Jensen, L., Nielsen, I. H., Mikkelsen, J. G. & Degn, S. E. (2025). Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments. Scandinavian Journal of Immunology, 102(2), Artikel e70043. https://doi.org/10.1111/sji.70043

Corydon, T. J. & Bek, T. (2025). Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration. Progress in Retinal and Eye Research, 104, Artikel 101323. https://doi.org/10.1016/j.preteyeres.2024.101323

Girault, V., Stukalov, A., Carter-Timofte, M. E., Hertzog, J., Verin, M., Austen, K., Haas, D. A., Oubraham, L., Piras, A., Maidl, S., Öllinger, R., Rad, R., Protzer, U., Kaufer, B. B., Lebbink, R. J., Rehwinkel, J., Mogensen, T. H. & Pichlmair, A. (2025). Multi-proteomic profiling of the varicella-zoster virus–host interface reveals host susceptibilities to severe infection. Nature Microbiology, 10(8), 2048-2072. https://doi.org/10.1038/s41564-025-02068-7

Boonkaew, S., Teodori, L., Vendelbo, M. H., Kjems, J. & Ferapontova, E. E. (2025). Nanobodies' duo facilitates ultrasensitive serum HER-2/neu immunoassays via enhanced avidity interactions. Analytica Chimica Acta, 1335, Artikel 343472. https://doi.org/10.1016/j.aca.2024.343472

Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J., Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025). Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake. npj biosensing, 2, Artikel 23. https://doi.org/10.1038/s44328-025-00042-1

Jensen, E. G., Jakobsen, T. S., Schnabolk, G., Wilson, K., Rask-Pedersen, M., Jensen, N., Andersen, G. R., Thiel, S., Aagaard, L., Rohrer, B., Askou, A. L. & Corydon, T. J. (2025). Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice. Molecular Therapy Methods and Clinical Development, 33(4), Artikel 101620. https://doi.org/10.1016/j.omtm.2025.101620

Lindholst, C., Andersen, C. U. & Sørensen, L. K. (2025). National kortlægning af rusmidler i spildevand fra danske byer. Aarhus Universitet. https://www.sst.dk/-/media/Opioider/Vidensbank/National-kortlaegning-af-rusmidler-i-spildevand-fra-danske-byer.ashx?sc_lang=da&hash=0C1F9E9BDDF4BD6665AD0D414348CB18

Iba, Y., Kubota, A., Takeda, Y., Derin, M. O., Ikegami, S., Mutterlose, J., Harada, T., Takeuchi, T. & Tainaka, K. (2025). Nature visible only digitally. Patterns, 6(4), Artikel 101210. https://doi.org/10.1016/j.patter.2025.101210

Joca, S. (2025). Neurodegenerative disorders: Advances in neurobiology and new treatment perspectives. Basic and Clinical Pharmacology and Toxicology, 136(1), Artikel e14098. https://doi.org/10.1111/bcpt.14098

Grønnebæk, T. S., Haahr-Lillevang, H., Skov, M., Kelly, K., Kerr, N. R., Viteri, J. A., Jaworek, A., Bartlett, A., Bold, J., Hutchison, J., Quiroz, J., Tankisi, H., Pedersen, T. H., Andersen, H. & Arnold, W. D. (2025). Neuromuscular transmission deficits in patients with CMT and ClC-1 inhibition in CMT animal models. Annals of Clinical and Translational Neurology, 12(2), 320-331. https://doi.org/10.1002/acn3.52252, https://doi.org/10.1002/acn3.52252

Santi, M. M., Genovese, E., Schou, T. M., da Silva, M., Erhardt, S., Schwieler, L., Weidenfors, J. A., Marino, G., Paludan, S. R., Joca, S., Wegener, G., Reinert, L. & Bay-Richter, C. (2025). Neuropsychiatric- and cognitive post-acute sequelae of SARS-CoV-2 infection - evidence from K18-hACE C57BL/6 J mice. The international journal of neuropsychopharmacology, 28(10), Artikel pyaf072. https://doi.org/10.1093/ijnp/pyaf072

Voloudakis, G., Therrien, K., Tomasi, S., Rajagopal, V. M., Choi, S. W., Demontis, D., Fullard, J. F., Børglum, A. D., O’Reilly, P. F., Hoffman, G. E. & Roussos, P. (2025). Neuropsychiatric polygenic scores are weak predictors of professional categories. Nature Human Behaviour, 9(3), 595-608. Artikel 2457. https://doi.org/10.1038/s41562-024-02074-5

Fritz, M., Rosa, P. B., Wilhelms, D., Jaarola, M., Ruud, J., Engblom, D. & Klawonn, A. M. (2025). Nicotinic α7 receptors on cholinergic neurons in the striatum mediate cocaine-reinforcement, but not food reward. Frontiers in Molecular Neuroscience, 17, Artikel 1418686. https://doi.org/10.3389/fnmol.2024.1418686, https://doi.org/10.3389/fnmol.2024.1418686

Aymerich, N., Bucheli, O. T. M., Portmann, K., Schlotheuber, L. J., Sigvaldadóttir, I., Baudry, J. & Eyer, K. (2025). Non-conjugated TLR agonists increase the quantity of antibodies but not their quality in a murine immunization model. Vaccine, 62, Artikel 127518. https://doi.org/10.1016/j.vaccine.2025.127518

Bedei, I., Bruder, J., Lund, I. C. B., Thomsen, S. H., Vogel, I., Maciel-Guerra, A. T., Alvarez-Nava, F., Crenshaw, M. L., Axt-Fliedner, R., Gravholt, C. H. & Skakkebæk, A. (2025). Non-Invasive Prenatal Testing by Cell-Free DNA (cfNIPT) for Detecting Turner Syndrome With Mosaicism and Structural Variants—Prenatal Findings and Postnatal Outcomes. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, 199(2), 124-133. https://doi.org/10.1002/ajmg.c.32136

Andersen-Civil, A. I. S., Mantel, M., Soh, J., Mostowy, S., Brugman, S. & Vanwalleghem, G. C. (2025). Novel and unscrutinized immune entities of the zebrafish gut. FEBS Letters, 599(23), 3444-3455. https://doi.org/10.1002/1873-3468.70161

Dmytriw, A. A., Butt, W., Blanc, R., Piotin, M., DeVries, J., Levrier, O., Papagiannaki, C., Buhk, J.-H., Mikkelsen, R., Al Raaisi, A., Redjem, H., Guedin, P., Milot, G., Chau, Y., Chow, M., Navasa, J. M., Naggara, O., Sedat, J., Desal, H.-A. ... Sorensen, L. (2025). Novel Delivery System Significantly Improves Technical Success and Safety of the Endovascular Clip System (eCLIPs) While Maintaining Efficacy for the Treatment of Wide-Necked Bifurcation Aneurysms: A Prospective, Multisite Registry. Neurosurgery, 97(4), 963-970. Artikel 10.1227/neu.0000000000003666. https://doi.org/10.1227/neu.0000000000003666

Actis Dato, V., Fujita, K. & Lange, S. (2025). Novel links of ATG4 proteases to cytoskeletal adapters of the obscurin protein family. Autophagy, 21(12), 3433-3435. https://doi.org/10.1080/15548627.2025.2572530

Donskov, J. G. (2025). Nuclear Receptor Signaling in Mental Illness. From Genetic Risk to Psychopathology. [Ph.d.-afhandling, Aarhus Universitet].

Hasan, S. S., John, D., Rudnicki, M., AlZaim, I., Eberhard, D., Moll, I., Taylor, J., Klein, C., von Heesen, M., Conradi, L. C., Adams, R. H., Lammert, E., Kalucka, J., Ruhrberg, C., Dimmeler, S. & Fischer, A. (2025). Obesity drives depot-specific vascular remodeling in male white adipose tissue. Nature Communications, 16(1), Artikel 5392. https://doi.org/10.1038/s41467-025-60910-2

Pioner, J. M., Pierantozzi, E., Coppini, R., Rubino, E. M., Biasci, V., Vitale, G., Laurino, A., Santini, L., Scardigli, M., Randazzo, D., Olianti, C., Serano, M., Rossi, D., Tesi, C., Cerbai, E., Lange, S., Reggiani, C., Sacconi, L., Poggesi, C. ... Sorrentino, V. (2025). Obscurin deficiency leads to compensated dilated cardiomyopathy and increased arrhythmias. Journal of General Physiology, 157(4), Artikel e202413696. https://doi.org/10.1085/jgp.202413696

Nielsen, S., Nyvad, J., Grove, E. L., Poulsen, P. L., Laugesen, E., Christensen, K. L. & Buus, N. H. (2025). Obstructive sleep apnea is associated with cardiac structural and functional alterations in patients with advanced diabetic kidney disease. Diabetes Research and Clinical Practice, 226, Artikel 112225. https://doi.org/10.1016/j.diabres.2025.112225

Gribsholt, S. B., Horváth-Puhó, E., Elser, H., Laugesen, K., Skajaa, N., Fuglsang, C. H., Henderson, V. & Sørensen, H. T. (2025). Obstructive sleep apnoea and risk of dementia: a Danish population-based cohort study. BMJ Neurology Open, 7(2), Artikel e001174. https://doi.org/10.1136/bmjno-2025-001174

Jensen, S. K., Bertelsen, M., Vestergaard, S. V., Nørgaard, M., Thomsen, R. W., Birn, H., Heide-Jørgensen, U. & Christiansen, C. F. (2025). Occurrence and prognosis of chronic kidney disease in Denmark-a nationwide population-based cohort study. Clinical Kidney Journal, 18(6), Artikel sfaf147. https://doi.org/10.1093/ckj/sfaf147

Fuglsang, C. H., Rasmussen, T. B., Rudolfsen, J. H., Olsen, J., Skipper, N., Ulrichsen, S. P., Sørensen, H. T. & Christiansen, C. F. (2025). Occurrence, mortality, and economic burden of brain disorders in Denmark, 2015–2021: a population-based cohort study. The Lancet Regional Health - Europe, 50, Artikel 101189. https://doi.org/10.1016/j.lanepe.2024.101189

Mitchell, C. W., Yuan, H., Sønderstrup-Jensen, M., Ferenbach, A. T. & van Aalten, D. M. F. (2025). O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control. Biology Open, 15(7), Artikel 250064. https://doi.org/10.1098/rsob.250064

Schulz, H., Abdelfattah, F., Heinrich, A., Melnik, D., Sandt, V., Krüger, M., Wehland, M., Hoffmann, P., Cortés-Sánchez, J. L., Evert, M., Evert, K. & Grimm, D. (2025). Omics Investigations of Prostate Cancer Cells Exposed to Simulated Microgravity Conditions. Biomolecules, 15(2), Artikel 303. https://doi.org/10.3390/biom15020303

Kollmann, C. F., van Montfoort, N., Cordelier, P., Pol, J. & Olagnier, D. (2025). Oncolytic virotherapy: Sparking durable anti-tumor immunity through microenvironment modulation. Seminars in Immunology, 80, Artikel 101994. https://doi.org/10.1016/j.smim.2025.101994

Olagnier, D. & Alain, T. (2025). Oncolytic viruses in action: A successful unique case to be considered with caution. Virologie , 29(4), 26-29. https://doi.org/10.1684/vir.2025.1097

Wedman, J. J., de Vries, L., van Lingen, B., van der Zwaag, M., Gómez-Sánchez, R., Hardenberg, R., Huibers, W., Permentier, H., Strauss, E., Chang, M., Reggiori, F., de Kroon, A. I., Sibon, O. C. M. & Schepers, H. (2025). Opt1 imports CoA precursors as glutathione mixed disulfides. The Journal of Biological Chemistry, 301(9), Artikel 110503. https://doi.org/10.1016/j.jbc.2025.110503

Fejerskov, O. & Manji, F. (2025). Oral Health Care - Past, Present and Future Perspectives. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 401-405). Wiley-Blackwell.

Mikkelsen, N. S., Ravendran, S., Broksø, A. D., Skjelbostad, S. F., Pedersen, M. G., Fang, H., Terkelsen, T., Thomsen, M. K. & Bak, R. O. (2025). Orthogonal CRISPR systems for targeted integration and multiplex base editing enable nonviral engineering of allogeneic CAR T cells. Molecular Therapy, 33(12), 6082-6100. https://doi.org/10.1016/j.ymthe.2025.08.032

Broksø, A. D., Bendixen, L., Fammé, S., Mikkelsen, K., Jensen, T. I. & Bak, R. O. (2025). Orthogonal transcriptional modulation and gene editing using multiple CRISPR/Cas systems. Molecular Therapy, 33(1), 71-89. https://doi.org/10.1016/j.ymthe.2024.11.024

Einarsson, H. B., Mortensen, A. F., Nielsen, M. S., Chen, M., Nielsen, S. R., Kraft, D. C. E., Jensen, J., Bjerre, M., Nygaard, J. V., Bünger, C. E. & Vorup-Jensen, T. (2025). Osteoclast-like multinucleated giant cells reinforce polycaprolactone grafts. Frontiers in Immunology, 16, Artikel 1572238. https://doi.org/10.3389/fimmu.2025.1572238

Alan Albayrak, E., Pinilla, E., Comerma Steffensen, S. G., Erac, Y., Yetik-Anacak, G., Simonsen, U. & Sevin, G. (2025). Osthole improves erectile function by increasing endogenous H2S production. European Journal of Pharmacology, 997, Artikel 177619. https://doi.org/10.1016/j.ejphar.2025.177619

Krarup, S., Bertelsen, J. B., Ovesen, T. & Zainali-Gill, K. (2025). Outcome of drug-induced sedation endoscopy in adults with obstructive sleep apnoea or snoring. Danish Medical Journal, 72(11), Artikel A04250284. https://doi.org/10.61409/A04250284

Andersen, C. Y., Donnez, J., Ernst, E., Gook, D., Pellicer, A., Von Wolff, M., Suzuki, N., Roux, C. & Dolmans, M.-M. (2025). Ovarian tissue cryopreservation in breast cancer patients: glass half empty or glass half full? Reproductive Biomedicine, 50(1), Artikel 104442. https://doi.org/10.1016/j.rbmo.2024.104442

Madan, E., Palma, A. M., Vudatha, V., Kumar, A., Bhoopathi, P., Wilhelm, J., Bernas, T., Martin, P. C., Bilolikar, G., Gogna, A., Peixoto, M. L., Dreier, I., Araujo, T. F., Garre, E., Gustafsson, A., Dorayappan, K. D. P., Mamidi, N., Sun, Z., Yekelchyk, M. ... Gogna, R. (2025). Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells. Nature Biotechnology, 43(11), 1833-1847. Artikel e13714. https://doi.org/10.1038/s41587-024-02453-3

Due, H., Brogaard, A., Issa, I. I., Jakobsen, M. Z., Sylvester, C., Nøhr, A. K., Thomsen, L. B., Thomsen, M. K., Brøndum, R. F. & Dybkær, K. (2025). Overexpression of CDCA2 in Diffuse Large B-Cell Lymphoma Promotes Cell Proliferation and Bortezomib Sensitivity. International Journal of Molecular Sciences , 26(12), Artikel 5596. https://doi.org/10.3390/ijms26125596

Ballin, M., Ekblom, Ö., Nordström, A., Ahlqvist, V. H. & Nordström, P. (2025). Overstated association between adolescent physical fitness and adulthood depression risk due to familial factors. Journal of Internal Medicine, 298(3), 200-213. https://doi.org/10.1111/joim.20109

Winokur, S. B., Caslin, A. Y., Davis, F. M. & Froemke, R. C. (2025). Oxytocin. Current Biology, 35(20), R985-R992. https://doi.org/10.1016/j.cub.2025.08.059

Risager, B. H., Mortensen, S., Pælestik, M. B., Lind, P. C., Stankovic, N. & Andersen, L. W. (2025). Patient Characteristics Associated With Outcomes After General Anaesthesia in Denmark: A Nationwide Observational Study. Acta Anaesthesiologica Scandinavica, 69(10), Artikel e70130. https://doi.org/10.1111/aas.70130

Leth, S. V., Graversen, S. B., Lisby, M., Støvring, H. & Sandbæk, A. (2025). Patients with repeated acute admissions to somatic departments: sociodemographic characteristics, disease burden, and contact with primary healthcare sector - a retrospective register-based case-control study. Scandinavian Journal of Public Health, 53(7), 689-697. https://doi.org/10.1177/14034948241230142

Suur, B. E., Karadimou, G., Willems, C. J. J. M., Bergman, O., Lengquist, M., Kronqvist, M., Baumgartner, R., Malin, S., Gisterå, A., Hansson, G. K., Mälarstig, A., Hedin, U., Ketelhuth, D. F. J. & Matic, L. (2025). PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis. Vascular Pharmacology, 159, Artikel 107490. https://doi.org/10.1016/j.vph.2025.107490

Janssen, N., van Polen, E. J., Daemen, J. H. T., Franssen, A. J. P. M., Hulsewé, K. W. E., Vissers, Y. L. J., Van Veer, H. G., de Paoli, F. V. & de Loos, E. R. (2025). Pectus excavatum revision surgery: a complex challenge requiring centralization of expertise. Journal of Thoracic Disease, 17(3), 1126-1130. https://doi.org/10.21037/jtd-24-1883

Gomez Del Val, A., Sánchez, A. B., Freire-Agulleiro, O., Pilar Martínez, M., Muñoz, M., Olmos, L., Sáenz-Medina, J., Comerma Steffensen, S. G., Simonsen, U., Rivera, L., López, M. F., Contreras, C. & Prieto, D. (2025). Penile endothelial dysfunction, impaired redox metabolism and blunted mitochondrial bioenergetics in diet-induced obesity: Compensatory role of H2O2. Free Radical Biology & Medicine, 230, 222-233. https://doi.org/10.1016/j.freeradbiomed.2025.02.004

Carvalho Sena de Almeida, J. O., Comerma Steffensen, S. G., Leite, J. R. D. S. D. A., Simonsen, U. & Arcanjo, D. D. R. (2025). Peptides from Animal Venoms: A Promising Frontier in Diabetes Therapy via Multi-Target Mechanisms. Pharmaceuticals, 18(10), 10. Artikel 1438. https://doi.org/10.3390/ph18101438

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