80 PURE

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Publikationsliste

Bak, R. O. & Porteus, M. H. (2017). CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors. Cell Reports, 20(3), 750-756. https://doi.org/10.1016/j.celrep.2017.06.064

Bonde, L., Shokouh, P., Jeppesen, P. B. & Boedtkjer, E. (2017). Crosstalk between cardiomyocyte-rich perivascular tissue and coronary arteries is reduced in the Zucker Diabetic Fatty rat model of type 2 diabetes mellitus. Acta Physiologica, 219(1), 227-238. https://doi.org/10.1111/apha.12685

Zevini, A., Olagnier, D. & Hiscottt, J. (2017). Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways. Trends in Immunology, 38(3), 194-205. https://doi.org/10.1016/j.it.2016.12.004

Jensen, A. K., Rechnitzer, C., Macklon, K. T., Ifversen, M. R. S., Birkebæk, N., Clausen, N., Sørensen, K., Fedder, J., Ernst, E. & Andersen, C. Y. (2017). Cryopreservation of ovarian tissue for fertility preservation in a large cohort of young girls: focus on pubertal development. Human Reproduction, 32(1), 154-164. https://doi.org/10.1093/humrep/dew273

Blondelle, J., Shapiro, P., Domenighetti, A. A. & Lange, S. (2017). Cullin E3 Ligase Activity Is Required for Myoblast Differentiation. Journal of Molecular Biology, 429(7), 1045-1066. https://doi.org/10.1016/j.jmb.2017.02.012

Grimm, D. (2017). Current Knowledge in Thyroid Cancer-From Bench to Bedside. International Journal of Molecular Sciences (Online), 18(7), Artikel 1529. https://doi.org/10.3390/ijms18071529

Pen, A. & Jensen, U. B. (2017). Current status of treating neurodegenerative disease with induced pluripotent stem cells. Acta Neurologica Scandinavica, 135(1), 57-72. https://doi.org/10.1111/ane.12545

Eriksson, K., Svensson, A., Hait, A. S., Schlüter, K., Tunbäck, P., Nordström, I., Padyukov, L., Liljeqvist, J.-Å., Mogensen, T. H. & Paludan, S. R. (2017). Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression. Journal of Immunology, 199(8), 2613-2617. https://doi.org/10.4049/jimmunol.1700385

Muñoz, M., López-Oliva, M. E., Pinilla, E., Martínez, M. P., Sánchez, A. B., Rodríguez, C., Garcia-Sacristán, A., Hernández, M., Rivera, L. & Prieto, D. (2017). CYP epoxygenase-derived H2O2 is involved in the endothelium-derived hyperpolarization (EDH) and relaxation of intrarenal arteries. Free Radical Biology & Medicine, 106, 168-183. https://doi.org/10.1016/j.freeradbiomed.2017.02.031

Warnke, E., Pietsch, J., Kopp, S., Bauer, J., Sahana, J., Wehland, M., Krüger, M., Hemmersbach, R., Infanger, M., Lützenberg, R. & Grimm, D. (2017). Cytokine Release and Focal Adhesion Proteins in Normal Thyroid Cells Cultured on the Random Positioning Machine. Cellular Physiology and Biochemistry, 43(1), 257-270. https://doi.org/10.1159/000480368

Enemark, H. L., Oksanen, A., Chriél, M., le Fèvre Harslund, J., Woolsey, I. D. & Al-Sabi, M. N. S. (2017). Detection and molecular characterization of the mosquito-borne filarial nematode Setaria tundra in Danish roe deer (Capreolus capreolus). International Journal for Parasitology: Parasites and Wildlife, 6(1), 16-21. https://doi.org/10.1016/j.ijppaw.2017.01.002

Møller, L. B., Schönewolf-Greulich, B., Rosengren, T., Larsen, L. J., Ostergaard, J. R., Sommerlund, M., Ostenfeldt, C., Stausbøl-Grøn, B., Linnet, K. M., Gregersen, P. A. & Jensen, U. B. (2017). Development of hypomelanotic macules is associated with constitutive activated mTORC1 in tuberous sclerosis complex. Molecular Genetics and Metabolism, 120(4), 384-391. https://doi.org/10.1016/j.ymgme.2017.02.008

Axelgaard, E., Østergaard, J. A., Thiel, S. & Hansen, T. K. (2017). Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin. Journal of Diabetes Research, Volume 2017, Artikel 6368780. https://doi.org/10.1155/2017/6368780

Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Buil, A., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, T. & Weinsheimer, S. (2017). Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome. Translational Psychiatry, 7(8), e1221. Artikel 1221. https://doi.org/10.1038/tp.2017.181

Skov Jensen, P., Aalkjaer, C. & Bek, T. (2017). Differential effects of nitric oxide and cyclo-oxygenase inhibition on the diameter of porcine retinal vessels with different caliber during hypoxia ex vivo. Experimental Eye Research, 160, 38-44. https://doi.org/10.1016/j.exer.2017.04.001

Farup, J., de Paoli, F. V., Giordani, L., Madaro, L., Puri, P. L. & Jessen, N. (2017). Differentiation of human fibro-adipogenic progenitors is associated with differential regulation of the non-coding RNAs in a COL1A1 dependent manner. Poster-session præsenteret på Gordon Research Conference, Italien.

Gantzel, R. H., Mogensen, L. S., Mikkelsen, S. A., Vilsen, B., Molday, R. S., Vestergaard, A. L. & Andersen, J. P. (2017). Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates. Scientific Reports, 7(1), 10418. Artikel doi: 10.1038/s41598-017-10741-z. https://doi.org/10.1038/s41598-017-10741-z

Møller, M., Rath, M. F., Ludvigsen, M., Honoré, B. & Vorum, H. (2017). Diurnal expression of proteins in the retina of the blind cone-rod homeobox (Crx(-/-) ) mouse and the 129/Sv mouse: a proteomic study. Acta Ophthalmologica, 7(95), 717-726. https://doi.org/10.1111/aos.13429

Sinturel, F. & Gachon, F. (2017). Diurnal liver mass is associated with ribosome biogenesis. OncoTarget, 8(57), 96476-96477. https://doi.org/10.18632/oncotarget.22255

Sinturel, F., Gerber, A., Mauvoisin, D., Wang, J., Gatfield, D., Stubblefield, J. J., Green, C. B., Gachon, F. & Schibler, U. (2017). Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles. Cell, 169(4), 651-663.e14. https://doi.org/10.1016/j.cell.2017.04.015

Hansen, A. S., Bundgaard, B., Biltoft, M., Rossen, L. S. & Höllsberg, P. (2017). Divergent tropism of HHV-6A_GS and HHV-6B_PL1 in T cells expressing different CD46 isoform patterns. Virology, 502, 160-170. https://doi.org/10.1016/j.virol.2016.12.027

Johannesen, M. D., Qvist, P., Lichota, J., Larsen, K. E., Nyegaard, M., Børglum, A. D. & Christensen, J. H. (2017). DNA Methylation Analysis of BRD1 Promoter Regions and the Schizophrenia rs138880 Risk Allele. PLoS One, 12(1), Artikel e0170121. https://doi.org/10.1371/journal.pone.0170121

Olesen, M. S., Starnawska, A., Agerholm, I., Forman, A., Overgaard, M. T. & Nyegaard, M. (2017). Does endometrial scratching change the biological age of the endometrium? -A paired prospective study. 312-312. Poster-session præsenteret på 33rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Geneva, Schweiz.

Ernst, E. H., Grøndahl, M. L., Grund, S., Hardy, K., Heuck, A., Sunde, L., Franks, S., Andersen, C. Y., Villesen, P. & Lykke-Hartmann, K. (2017). Dormancy and activation of human oocytes from primordial and primary follicles: molecular clues to oocyte regulation. Human Reproduction, 32(8), 1684-1700. https://doi.org/10.1093/humrep/dex238

Comerma Steffensen, S. G., Hedegaard, E. R., Kun, A., Mogensen, S., Aalkjær, C., Köhler, R., Christensen, B. M. & Simonsen, U. (2017). Down-regulation of KCa2.3 channels causes erectile dysfunction in mice. Scientific Reports, 7(1), Artikel 3839. https://doi.org/10.1038/s41598-017-04188-5

Kragstrup, T. W., Lomholt, S., Nielsen, M. A., Heftdal, L. D., Schafer, P. H. & Deleuran, B. (2017). Downstream Effects of Apremilast in Human Arthritic Ex Vivo Models. Arthritis and Rheumatology, 69, Artikel 642.

Eskelund, A., Li, Y., Budac, D. P., Müller, H. K., Gulinello, M., Sanchez, C. & Wegener, G. (2017). Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior. Journal of Neurochemistry, 142(1), 118-131. https://doi.org/10.1111/jnc.14043

Kolding, L., Sandager, P., Petersen, O. B., Uldbjerg, N. & Pedersen, L. H. (2017). Drug use in pregnancy – and effects in the cardiac function of the fetus. Poster-session præsenteret på 1st Annual Research Meeting, Dpt. of Clinical Medicine, Aarhus University.

Dyla, M., Terry, D., Kjærgaard, M., Sørensen, T. L.-M., Andersen, J. L., Andersen, J. P., Knudsen, C. R., Altman, R., Nissen, P. & Blanchard, S. (2017). Dynamics of P-type ATPase transport cycle revealed by single-molecule FRET. Nature, 551(7680), 346-351. https://doi.org/10.1038/nature24296

Phan, J.-A., Stokholm, K., Zareba-Paslawska, J., Jakobsen, S., Vang, K., Gjedde, A., Landau, A. M. & Romero-Ramos, M. (2017). Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease. Scientific Reports, 7(1), Artikel 6363. https://doi.org/10.1038/s41598-017-06724-9

Dørflinger, G. H., Holt, C. B., Thiel, S., Østergaard, J. A. & Hansen, T. K. (2017). Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes. Journal of Diabetes Research, 2017, Artikel 1249729. https://doi.org/10.1155/2017/1249729

Navne, J. E., Koch, A., Slotved, H. C., Andersson, M., Melbye, M., Ladefoged, K. & Børresen, M. (2017). Effect of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage by respiratory pathogens among greenlandic children. International journal of circumpolar health, 76(1), 1-8. https://doi.org/10.1080/22423982.2017.1309504

Randrup Hansen, C., Grimm, D. G., Bauer, J., Wehland, M. & Magnusson, N. E. (2017). Effects and Side Effects of Using Sorafenib and Sunitinib in the Treatment of Metastatic Renal Cell Carcinoma. International Journal of Molecular Sciences (Online), 18(2), Artikel 461. https://doi.org/10.3390/ijms18020461

Voss, T. S., Vendelbo, M. H., Opstrup, U. K., Pedersen, S. B., Nielsen, T. S., Johannsen, M., Svart, M. V., Jessen, N. & Møller, N. (2017). Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study. Diabetologia, 60(1), 143-152. https://doi.org/10.1007/s00125-016-4126-x

Ramshanker, N., Aagaard, M., Hjortebjerg, R., Voss, T. S., Møller, N., Jørgensen, J. O. L., Jessen, N., Bjerring, P., Magnusson, N. E., Bjerre, M., Oxvig, C. & Frystyk, J. (2017). Effects of prednisolone on serum and tissue fluid IGF-I receptor activation and post-receptor signaling in humans. Journal of Clinical Endocrinology and Metabolism, 102(11), 4031-4040. https://doi.org/10.1210/jc.2017-00696

Kampmann, U., Mathiassen, O. N., Christensen, K. L., Buus, N. H., Bjerre, M., Vase, H., Møller, N., Kaltoft, A. & Poulsen, P. L. (2017). Effects of Renal Denervation on Insulin Sensitivity and Inflammatory Markers in Nondiabetic Patients with Treatment-Resistant Hypertension. Journal of Diabetes Research, 2017, 1-9. Artikel 6915310. https://doi.org/10.1155/2017/6915310, https://doi.org/10.1155/2017/6915310

Simonsen, U., Wandall-Frostholm, C., Oliván-Viguera, A. & Köhler, R. (2017). Emerging roles of calcium-activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse. Acta Physiologica, 219(1), 176–187. https://doi.org/10.1111/apha.12768

Rajkumar, A. P., Horsdal, H. T., Wimberley, T., Cohen, D., Mors, O., Børglum, A. D. & Gasse, C. (2017). Endogenous and Antipsychotic-Related Risks for Diabetes Mellitus in Young People With Schizophrenia: A Danish Population-Based Cohort Study. American Journal of Psychiatry, 174(7), 686-694. https://doi.org/10.1176/appi.ajp.2016.16040442

Mortensen, S. A., Skov, L. L., Kjaer-Sorensen, K., Hansen, A. G., Hansen, S., Dagnæs-Hansen, F., Jensenius, J. C., Oxvig, C., Thiel, S. & Degn, S. E. (2017). Endogenous Natural Complement Inhibitor Regulates Cardiac Development. Journal of Immunology, 198(8), 3118-3126. https://doi.org/10.4049/jimmunol.1601958

To, E. E., Vlahos, R., Luong, R., Halls, M. L., Reading, P. C., King, P. T., Chan, C., Drummond, G. R., Sobey, C. G., Broughton, B. R. S., Starkey, M. R., van der Sluis, R., Lewin, S. R., Bozinovski, S., O'Neill, L. A. J., Quach, T., Porter, C. J. H., Brooks, D. A., O'Leary, J. J. & Selemidis, S. (2017). Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy. Nature Communications, 8(1), 69. Artikel 69. https://doi.org/10.1038/s41467-017-00057-x

Eriksen, P. L., Kreutzfeldt, M., Grønbaek, H., Thorsen, K., Vang, S., Jessen, N. & Vilstrup, H. (2017). Enrichment of Genetic Variants in the Glucocorticoid Receptor Signalling Pathway in Autoimmune Hepatitis with Failure of Standard Treatment. Basic and Clinical Pharmacology and Toxicology, 121(3), 189-194. https://doi.org/10.1111/bcpt.12788

Chandrawati, R., Olesen, M. T. J., Marini, T. C. C., Bisra, G., Guex, A. G., de Oliveira, M. G., Zelikin, A. N. & Stevens, M. M. (2017). Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics. Advanced Healthcare Materials, 6(17), Artikel 1700385. https://doi.org/10.1002/adhm.201700385

Nielsen, H. M., Andersen, C. L., Westman, M., Kristensen, L. S., Asmar, F., Kruse, T. A., Thomassen, M., Larsen, T. S., Skov, V., Hansen, L. L., Bjerrum, O. W., Hasselbalch, H. C., Punj, V. & Gronbaek, K. (2017). Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations. Scientific Reports, 7(1), Artikel 6774. https://doi.org/10.1038/s41598-017-07057-3

Starnawska, A., Tan, Q., McGue, M., Mors, O., Borglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L. (2017). Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins. Frontiers in Aging Neuroscience, 9(DEC), Artikel 413. https://doi.org/10.3389/fnagi.2017.00413

Masud, H. M. A. A., Watanabe, T., Yoshida, M., Sato, Y., Goshima, F., Kimura, H. & Murata, T. (2017). Epstein-Barr virus BKRF4 gene product is required for efficient progeny production. Journal of Virology, 91(23), Artikel e00975-17. https://doi.org/10.1128/JVI.00975-17

Jensen, A. K., Macklon, K. T., Fedder, J., Ernst, E., Humaidan, P. & Andersen, C. Y. (2017). Erratum to: 86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: focus on birth and perinatal outcome in 40 of these children. Journal of Assisted Reproduction and Genetics, 34(3), 337. https://doi.org/10.1007/s10815-017-0873-y

Støvring, H., Pottegård, A. & Hallas, J. (2017). Estimating medication stopping fraction and real-time prevalence of drug use in pharmaco-epidemiologic databases. An application of the reverse waiting time distribution. Pharmacoepidemiology and Drug Safety, 26(8), 909-916. https://doi.org/10.1002/pds.4217

Olagnier, D., Chiang, C. & Hiscott, J. (2017). Evaluation of Innate Immune Gene Expression Following HDAC Inhibitor Treatment by High Throughput qPCR and PhosFlow Cytometry. Methods in molecular biology (Clifton, N.J.), 1510, 245-255. https://doi.org/10.1007/978-1-4939-6527-4_18

Kuchenbaecker, K. B., McGuffog, L., Barrowdale, D., Lee, A., Soucy, P., Dennis, J., Domchek, S. M., Robson, M., Spurdle, A. B., Ramus, S. J., Mavaddat, N., Terry, M. B., Neuhausen, S. L., Schmutzler, R. K., Simard, J., Pharoah, P. D. P., Offit, K., Couch, F. J., Chenevix-Trench, G. ... Jensen, U. B. (2017). Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers. Journal of the National Cancer Institute, 109(7). https://doi.org/10.1093/jnci/djw302