80 PURE

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Personliste

Publikationsliste

Stewart, T. A. & Davis, F. M. (2019). Formation and Function of Mammalian Epithelia: Roles for Mechanosensitive PIEZO1 Ion Channels. Frontiers in Cell and Developmental Biology, 7, Artikel 260. https://doi.org/10.3389/fcell.2019.00260

Kilian, M. (2019). Fra taksonomi til klinik og vice versa. I N. Nørskov-Lauritsen & H. J. Kolmos (red.), Dansk Selskab for Klinisk Mikrobiologi 1969-2019 (s. 30-33). Syddansk Universitetsforlag. https://dskm.dk/wp-content/uploads/2019/09/Jubilæumsbog.pdf

Andersen, L. L., Terczyńska-Dyla, E., Mørk, N., Scavenius, C., Enghild, J. J., Höning, K., Hornung, V., Christiansen, M., Mogensen, T. H. & Hartmann, R. (2019). Frequently used bioinformatics tools overestimate the damaging effect of allelic variants. Genes and Immunity, 20(1), 10-22. https://doi.org/10.1038/s41435-017-0002-z

Richner, M., Ferreira, N., Dudele, A., Jensen, T. S., Vaegter, C. B. & Gonçalves, N. P. (2019). Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy. Frontiers in Neuroscience, 12, Artikel 1038. https://doi.org/10.3389/fnins.2018.01038

Roenn, C. P., Li, M., Schack, V. R., Forster, I. C., Holm, R., Toustrup-Jensen, M. S., Andersen, J. P., Petrou, S. & Vilsen, B. (2019). Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. Journal of Biological Chemistry, 294(1), 269-280. https://doi.org/10.1074/jbc.RA118.004591

Lin, L. & Luo, Y. (2019). Functional Evaluation of CRISPR Activity by the Dual-Fluorescent Surrogate System: C-Check. I Y. Luo (red.), Methods in Molecular Biology: Methods and Protocols (s. 67-77). Springer Science+Business Media. https://doi.org/10.1007/978-1-4939-9170-9_5

Pacheco-Torres, J., Moreno, A., Fernández, B., Pérez-Cervera, L., Caramés, J. M., Fernández-Mollá, L. M., Pérez-Montoyo, E., Martínez-Sánchez, M., Moratal, D. & Canals, S. (2019). Functional MRI of Synaptic Plasticity. https://doi.org/10.1016/B978-0-12-812028-6.00024-0

Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., Demontis, D., Børglum, A. D. ... iPSYCH-GEMS Schizophrenia Working Group (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51(4), 659-674. https://doi.org/10.1038/s41588-019-0364-4

Dorado, B., Pløen, G. G., Barettino, A., Macías, A., Gonzalo, P., Andrés-Manzano, M. J., González-Gómez, C., Galán-Arriola, C., Alfonso, J. M., Lobo, M., López-Martín, G. J., Molina, A., Sánchez-Sánchez, R., Gadea, J., Sánchez-González, J., Liu, Y., Callesen, H., Filgueiras-Rama, D., Ibáñez, B. ... Andrés, V. (2019). Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome. Cell Discovery, 5, Artikel 16. https://doi.org/10.1038/s41421-019-0084-z

Simonsen, U. (2019). Generelle principper for lægemidlers virkningsmekanisme. I K. Brøsen, U. Simonsen & K. Dahlhoff (red.), Basal og klinisk farmakologi (6. udg., s. 28-48). FADL's Forlag.

Væth, S., Christensen, R., Dunø, M., Lildballe, D. L., Thorsen, K., Vissing, J., Svenstrup, K., Hertz, J. M., Andersen, H. & Jensen, U. B. (2019). Genetic analysis of Charcot-Marie-Tooth disease in Denmark and the implementation of a next generation sequencing platform. European Journal of Medical Genetics, 62(1), 1-8. https://doi.org/10.1016/j.ejmg.2018.04.003

Hübel, C., Gaspar, H. A., Coleman, J. R. I., Hanscombe, K. B., Purves, K., Prokopenko, I., Graff, M., Ngwa, J. S., Workalemahu, T., O’Reilly, P. F., Bulik, C. M., Breen, G., ADHD Working Group of the Psychiatric Genomics Consortium, Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium ... International Headache Genetics Consortium (2019). Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent. Nature Communications, 10(1), Artikel 5765. https://doi.org/10.1038/s41467-019-13544-0

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC , Agrawal, A., Borglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R. ... Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 49(7), 1166-1173. https://doi.org/10.1017/S0033291718002039

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC , Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R. ... Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls - CORRIGENDUM. Psychological Medicine, 49(2), 351. https://doi.org/10.1017/S0033291718002945

Klein, M., Walters, R. K., Demontis, D., Stein, J. L., Hibar, D. P., Adams, H. H., Bralten, J., Mota, N. R., Schachar, R., Sonuga-Barke, E., Mattheisen, M., Neale, B. M., Thompson, P. M., Medland, S. E., Børglum, A. D., Faraone, S. V., Arias-Vasquez, A. & Franke, B. (2019). Genetic markers of ADHD-related variations in intracranial volume. American Journal of Psychiatry, 176(3), 228-238. https://doi.org/10.1176/appi.ajp.2018.18020149

Mikkelsen, R. B., Frederiksen, H. R. S., Gjerris, M., Holst, B., Hyttel, P., Luo, Y., Freude, K. & Sandøe, P. (2019). Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing. The CRISPR Journal, 2(6), 362-369. https://doi.org/10.1089/crispr.2019.0024

Buskbjerg, C. D. R., Amidi, A., Demontis, D., Nissen, E. R. & Zachariae, R. (2019). Genetic risk factors for cancer-related cognitive impairment: a systematic review. Acta Oncologica, 58(5), 537-547. https://doi.org/10.1080/0284186X.2019.1578410

Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B. ... Meltzer-Brody, S. (2019). Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders. Translational Psychiatry, 9(1), 288. Artikel 288. https://doi.org/10.1038/s41398-019-0629-9

Rohde, P. D., Jensen, I. R., Sarup, P. M., Ørsted, M., Demontis, D., Sørensen, P. & Kristensen, T. N. (2019). Genetic Signatures of Drug Response Variability in Drosophila melanogaster. Genetics (Print), 213(2), 633-650. https://doi.org/10.1534/genetics.119.302381

Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, T., Nordentoft, M., Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O. (2019). Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study. Archives of General Psychiatry, 76(9), 924-932. https://doi.org/10.1001/jamapsychiatry.2019.1119

Asad, J., Richner, M., Vægter, C. B., Nyengaard, J. R. & Jensen, P. H. (2019). Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9. Neuroscience Insights, 14(November-December), 1-12. https://doi.org/10.1177/1179069519889022

Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L. ... eQTLGen Consortium (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51(5), 793-803. https://doi.org/10.1038/s41588-019-0397-8

Anorexia Nervosa Genetics Initiative (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51(8), 1207-1214. https://doi.org/10.1038/s41588-019-0439-2

Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A. ... Børglum, A. D. (2019). Genome-wide association study implicates CHRNA2 in cannabis use disorder. Nature Neuroscience, 22, 1066-1074. https://doi.org/10.1038/s41593-019-0416-1

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. Translational Psychiatry, 9(1), Artikel 14. https://doi.org/10.1038/s41398-018-0360-y

Howard, D. M., Adams, M. J., Clarke, T.-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J. ... 23andMe Research Team (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nature Neuroscience, 22(3), 343-352. https://doi.org/10.1038/s41593-018-0326-7

Cross-Disorder Group of the Psychiatric Genomics Consortium (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell, 179(7), 1469-1482.e11. https://doi.org/10.1016/j.cell.2019.11.020

Hübel, C., Gaspar, H. A., Coleman, J. R. I., Finucane, H., Purves, K. L., Hanscombe, K. B., Prokopenko, I., Graff, M., Ngwa, J. S., Workalemahu, T., O'Reilly, P. F., Bulik, C. M., Breen, G., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, MAGIC Investigators & Eating Disorders Working Group of the Psychiatric Genomics Consortium (2019). Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 180(6), 428-438. https://doi.org/10.1002/ajmg.b.32709

Butt, S. A., Kelstrup, L., Lidang, M., Bertelsen, M., Ejrnæs, K., Sunde, L. & Perin, T. L. (2019). Gentagne diploid biparental molae. Ugeskrift for Læger, 181, Artikel V02190144.

Bomholt Larsen, A. S., Skydsgaard, M. A. & Kirkfeldt, S. S. (2019). Gentest og tandbørster. Hvordan sundhed blev fælles. 2D/3D (Fysisk produkt)

Murphy, R. A., Hill Christiansen, S., Sabnis, A., Schelenz, S., Vorup-Jensen, T., Davies, J. C. & Edwards, A. (2019). GLATIRAMER ACETATE IS AN ANTIBIOTIC RESISTANCE BREAKER AGAINST CYSTIC FIBROSIS STRAINS OF PSEUDOMONAS AERUGINOSA VIA DISRUPTION OF THE BACTERIAL OUTER MEMBRANE. S297-298. https://doi.org/10.1002/ppul.22495

Yucel, N., Wang, Y. X., Mai, T., Porpiglia, E., Lund, P. J., Markov, G., Garcia, B. A., Bendall, S. C., Angelo, M. & Blau, H. M. (2019). Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function. Cell Reports, 27(13), 3939-3955.e6. https://doi.org/10.1016/j.celrep.2019.05.092

Winther, G., Eskelund, A., Richter, C. B., Elfving, B., Müller, H. K., Lund, S. & Wegener, G. (2019). Grandmaternal High-fat Diet Primed Anxiety-like Behaviour in the Second-Generation Female Offspring. Behavioural Brain Research, 359, 47-55. https://doi.org/10.1016/j.bbr.2018.10.017

Therkildsen, M., Rasmussen, M. K., Jensen, J. A., Andersen, E. S., Møller, H. S., Jensen, S. K. & Stødkilde-Jørgensen, L. (2019). GreenPork: Kan det ses og smages, når slagtesvin fodres med græsprotein?. Poster-session præsenteret på Food Festival, Aarhus, Danmark.

Krüger, M., Kopp, S., Wehland, M., Bauer, J., Baatout, S., Moreels, M., Egli, M., Corydon, T. J., Infanger, M. & Grimm, D. (2019). Growing blood vessels in space: Preparation studies of the SPHEROIDS project using related ground-based studies. Acta Astronautica, 159, 267-272. https://doi.org/10.1016/j.actaastro.2019.03.074

Sharma, V. M., Vestergaard, E. T., Jessen, N., Kolind-Thomsen, P., Nellemann, B., Nielsen, T. S., Vendelbo, M. H., Møller, N., Sharma, R., Lee, K. Y., Kopchick, J. J., Jørgensen, J. O. L. & Puri, V. (2019). Growth hormone acts along PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes. A J P: Endocrinology and Metabolism (Online), 316(1), E34-E42. https://doi.org/10.1152/ajpendo.00129.2018

Høgild, M. L., Bak, A. M., Pedersen, S. B., Rungby, J., Frystyk, J., Møller, N., Jessen, N. & Jørgensen, J. O. L. (2019). Growth Hormone Signaling and Action in Obese versus Lean Human Subjects. American Journal of Physiology: Endocrinology and Metabolism, 316(2), E333-E344. https://doi.org/10.1152/ajpendo.00431.2018

Krüger, M., Pietsch, J., Bauer, J., Kopp, S., Carvalho, D. T. O., Baatout, S., Moreels, M., Melnik, D., Wehland, M., Egli, M., Jayashree, S., Kobberø, S. D., Corydon, T. J., Nebuloni, S., Gass, S., Evert, M., Infanger, M. & Grimm, D. (2019). Growth of Endothelial Cells in Space and in Simulated Microgravity - a Comparison on the Secretory Level. Cellular Physiology and Biochemistry, 52(5), 1039-1060. https://doi.org/10.33594/000000071

Braun, E., Hotter, D., Koepke, L., Zech, F., Groß, R., Sparrer, K. M. J., Müller, J. A., Pfaller, C. K., Heusinger, E., Wombacher, R., Sutter, K., Dittmer, U., Winkler, M., Simmons, G., Jakobsen, M. R., Conzelmann, K.-K., Pöhlmann, S., Münch, J., Fackler, O. T. ... Sauter, D. (2019). Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins. Cell Reports, 27(7), 2092-2104.e10. https://doi.org/10.1016/j.celrep.2019.04.063

Grimm, D. (2019). Guest Edited Collection: Gravitational biology and space medicine. Scientific Reports, 9(1), Artikel 14399. https://doi.org/10.1038/s41598-019-51231-8

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., Anjorin, A., Corvin, A., Sanders, A. R., Forstner, A. J., Reif, A., Koller, A. C., Tkowska, B. S., Baune, B. T., Müller-Myhsok, B. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium (2019). GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores. American Journal of Psychiatry, 176(8), 651-660. https://doi.org/10.1176/appi.ajp.2019.18080957

Sædder, E. A., Thomsen, A. H., Hasselstrøm, J. B. & Jornil, J. R. (2019). Heart insufficiency after combination of verapamil and metoprolol: A fatal case report and literature review. Clinical Case Reports, 7(11), 2042-2048. https://doi.org/10.1002/ccr3.2393

Sundelin, E. I. O., Gormsen, L. C., Heebøll, S., Vendelbo, M. H., Jakobsen, S., Munk, O. L., Feddersen, S., Brøsen, K., Hamilton-Dutoit, S. J., Pedersen, S. B., Grønbaek, H. & Jessen, N. (2019). Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease. British Journal of Clinical Pharmacology, 85(8), 1761-1770. https://doi.org/10.1111/bcp.13962

Bavafaye Haghighi, E., Knudsen, M., Laursen, B. E. & Besenbacher, S. (2019). Hierarchical classification of cancers of unknown primary using multi-omics data. Cancer Informatics, 18. https://doi.org/10.1177/1176935119872163

Laursen, M. B., Reinholdt, L., Schönherz, A. A., Due, H., Jespersen, D. S., Grubach, L., Ettrup, M. S., Røge, R., Falgreen, S., Sørensen, S., Bødker, J. S., Schmitz, A., Johnsen, H. E., Bøgsted, M. & Dybkær, K. (2019). High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients. OncoTarget, 10(7), 717-731. https://doi.org/10.18632/oncotarget.26588

Skov, S. T., Bünger, C., Rölfing, J. H. D., Hansen, E. S., Høy, K., Valancius, K., Helmig, P. & Haisheng, L. (2019). High global satisfaction in magnetically controlled elongations in 29 early-onset scoliosis patients versus primary spinal fusion in 20 adolescent idiopathic scoliosis patients. Open Journal of Orthopedics and Rheumatology, 4(1), 005-009. https://doi.org/10.17352/ojor.000018

Madsen, C., Lauridsen, K. L., Plesner, T. L., Monrad, I., Honoré, B., Hamilton-Dutoit, S., d’Amore, F. & Ludvigsen, M. (2019). High intratumoral expression of vimentin predicts histological transformation in patients with follicular lymphoma. Blood Cancer Journal, 9(4), Artikel 35. https://doi.org/10.1038/s41408-019-0197-5

Wen, L., Zhao, Z., Wang, Z., Xiao, J., Birn, H. & Gregersen, J. W. (2019). High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy. Nephrology, 24(7), 703-710. https://doi.org/10.1111/nep.13477

Martin, R. M., Ikeda, K., Cromer, M. K., Uchida, N., Nishimura, T., Romano, R., Tong, A. J., Lemgart, V. T., Camarena, J., Pavel-Dinu, M., Sindhu, C., Wiebking, V., Vaidyanathan, S., Dever, D. P., Bak, R. O., Laustsen, A., Lesch, B. J., Jakobsen, M. R., Sebastiano, V. ... Porteus, M. H. (2019). Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. Cell Stem Cell, 24(5), 821-828.e5. https://doi.org/10.1016/j.stem.2019.04.001

Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), Artikel 4627. https://doi.org/10.1038/s41467-019-12236-z

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