80 PURE

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Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O. ... Eley, T. C. (2020). A major role for common genetic variation in anxiety disorders. Molecular Psychiatry, 25, 3292-3303. https://doi.org/10.1038/s41380-019-0559-1

Mose, M., Rittig, N., Mikkelsen, U. R., Jessen, N., Bengtsen, M. B., Christensen, B., Jørgensen, J. O. L. & Møller, N. (2020). A model mimicking catabolic inflammatory disease; a controlled randomized study in humans. PLoS One, 15(11), Artikel e0241274. https://doi.org/10.1371/journal.pone.0241274

Butt, L., Unnersjö-Jess, D., Höhne, M., Edwards, A., Binz-Lotter, J., Reilly, D., Hahnfeldt, R., Ziegler, V., Fremter, K., Rinschen, M. M., Helmstädter, M., Ebert, L. K., Castrop, H., Hackl, M. J., Walz, G., Brinkkoetter, P. T., Liebau, M. C., Tory, K., Hoyer, P. F. ... Benzing, T. (2020). A molecular mechanism explaining albuminuria in kidney disease. Nature Metabolism, 2(5), 461-474. https://doi.org/10.1038/s42255-020-0204-y

Sjöstedt, E., Zhong, W., Fagerberg, L., Karlsson, M., Mitsios, N., Adori, C., Oksvold, P., Edfors, F., Limiszewska, A., Hikmet, F., Huang, J., Du, Y., Lin, L., Dong, Z., Yang, L., Liu, X., Jiang, H., Xu, X., Wang, J. ... Mulder, J. (2020). An atlas of the protein-coding genes in the human, pig, and mouse brain. Science, 367(6482), Artikel 5947. https://doi.org/10.1126/science.aay5947

Huber, J., Obata, M., Gruber, J., Akutsu, M., Löhr, F., Rogova, N., Güntert, P., Dikic, I., Kirkin, V., Komatsu, M., Dötsch, V. & Rogov, V. V. (2020). An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16(2), 256-270. https://doi.org/10.1080/15548627.2019.1606637

Liu, Y., Xu, W., Huang, Z. H., Guo, J., Fedosova, N. & Jiang, R. W. (2020). An Efficient Strategy for the Chemo-Enzymatic Synthesis of Bufalin Glycosides with Improved Water Solubility and Inhibition against Na⁺, K⁺-ATPase. Chemistry and Biodiversity, 17(11), Artikel e2000529. https://doi.org/10.1002/cbdv.202000529

Toft, G., Heide-Jørgensen, U., van Haalen, H., James, G., Hedman, K., Birn, H., Christiansen, C. F. & Thomsen, R. W. (2020). Anemia and clinical outcomes in patients with non-dialysis dependent or dialysis dependent severe chronic kidney disease: a Danish population-based study. Journal of Nephrology, 33(1), 147-156. https://doi.org/10.1007/s40620-019-00652-9

Wehland, M., Simonsen, U., Buus, N. H., Krüger, M. & Grimm, D. (2020). An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension. Expert Opinion on Pharmacotherapy, 21(10), 1133-1143. https://doi.org/10.1080/14656566.2020.1735356

Gregersen, P. A., McKay, V., Walsh, M., Brown, E., McGillivray, G. & Savarirayan, R. (2020). A new case of Greenberg dysplasia and literature review suggest that Greenberg dysplasia, dappled diaphyseal dysplasia, and Astley–Kendall dysplasia are allelic disorders. Molecular Genetics and Genomic Medicine, 8(6), Artikel e1173. https://doi.org/10.1002/mgg3.1173

Bordoni, L., Jiménez, E. G., Nielsen, S., Østergaard, L. & Frische, S. (2020). A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics. Experimental animals, 69(1), 92-103. https://doi.org/10.1538/expanim.19-0040

23andMe Research Team & Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium (2020). An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression. American Journal of Psychiatry, 177(10), 944-954. https://doi.org/10.1176/appi.ajp.2020.19111158

Brent, M. B., Brüel, A. & Thomsen, J. S. (2020). Animal models of disuse-induced bone loss: study protocol for a systematic review. Systematic Reviews, 9(1), Artikel 185. https://doi.org/10.1186/s13643-020-01441-3

Xue, J., Thomas, L., Tahmasbi, M., Valdez, A., Dominguez Rieg, J. A., Fenton, R. A. & Rieg, T. (2020). An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea. Clinical Science, 134(8), 941-953. https://doi.org/10.1042/CS20200065

Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H., Kalucka, J., Sokol, L., García-Caballero, M., Zheng, Y., Qian, J., Teuwen, L.-A., Khan, S., Boeckx, B., Wauters, E., Decaluwé, H., De Leyn, P. ... Carmeliet, P. (2020). An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. Cancer Cell, 37(1), 21-36.e13. https://doi.org/10.1016/j.ccell.2019.12.001

Bie, A. S., Cömert, C., Körner, R., Corydon, T. J., Palmfeldt, J., Hipp, M. S., Hartl, F. U. & Bross, P. (2020). An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space. Cell Stress & Chaperones, 25(3), 407-416. https://doi.org/10.1007/s12192-020-01080-6

Damsgaard, C., Lauridsen, H., Harter, T. S., Kwan, G. T., Thomsen, J. S., Funder, A. M. D., Supuran, C. T., Tresguerres, M., Matthews, P. GD. & Brauner, C. J. (2020). A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina. eLife, 9, 1-20. Artikel e58995. https://doi.org/10.7554/eLife.58995

Wang, J., Zhang, X., Cheng, L. & Luo, Y. (2020). An overview and metanalysis of Machine and Deep Learning-Based CRISPR gRNA Design Tools. RNA Biology, 17(1), 13-22. https://doi.org/10.1080/15476286.2019.1669406

Jensen, J. M. B. & Sørensen, U. (2020). Antistoffer. I Immunologi (s. 135-147)

Watanabe, T., Sato, Y., Masud, H. M. A. A., Takayama, M., Matsuda, H., Hara, Y., Yanagi, Y., Yoshida, M., Goshima, F., Murata, T. & Kimura, H. (2020). Antitumor activity of cyclin-dependent kinase inhibitor alsterpaullone in Epstein-Barr virus-associated lymphoproliferative disorders. Cancer Science, 111(1), 279-287. https://doi.org/10.1111/cas.14241

Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C. & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. Journal of Immunology, 205(6), 1678-1694. https://doi.org/10.4049/jimmunol.2000528

Matchkov, V. V., Black Joergensen, H., Kamaev, D., Hoegh Jensen, A., Beck, H. C., Skryabin, B. V. & Aalkjaer, C. (2020). A paradoxical increase of force development in saphenous and tail arteries from heterozygous ANO1 knockout mice. Physiological Reports, 8(22), Artikel e14645. https://doi.org/10.14814/phy2.14645

Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T.-K., Deary, I. J., Whalley, H. C., McIntosh, A. M., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J. H. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11(1), 2301. Artikel 2301. https://doi.org/10.1038/s41467-020-16022-0

Uzureau, S., Lecordier, L., Uzureau, P., Hennig, D., Graversen, J. H., Homblé, F., Mfutu, P. E., Oliveira Arcolino, F., Ramos, A. R., La Rovere, R. M., Luyten, T., Vermeersch, M., Tebabi, P., Dieu, M., Cuypers, B., Deborggraeve, S., Rabant, M., Legendre, C., Moestrup, S. K. ... Pays, E. (2020). APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin. Cell Reports, 30(11), 3821-3836.e13. https://doi.org/10.1016/j.celrep.2020.02.064

Asaro, A., Carlo-Spiewok, A.-S., Malik, A. R., Rothe, M., Schipke, C. G., Peters, O., Heeren, J. & Willnow, T. E. (2020). Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling. Alzheimer's & dementia : the journal of the Alzheimer's Association, 16(9), 1248-1258. https://doi.org/10.1002/alz.12121

Seo, J. A., Kang, M.-C., Yang, W.-M., Hwang, W. M., Kim, S. S., Hong, S. H., Heo, J.-I., Vijyakumar, A., Pereira de Moura, L., Uner, A., Huang, H., Lee, S. H., Lima, I. S., Park, K. S., Kim, M. S., Dagon, Y., Willnow, T. E., Aroda, V., Ciaraldi, T. P. ... Kim, Y.-B. (2020). Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity. Nature Communications, 11(1), 2024. Artikel 2024. https://doi.org/10.1038/s41467-020-15963-w

Bordoni, L., Sardella, D. & Schiessl, I. M. (2020). A Porthole over AKI: Cell Dynamics in Damage and Repair. Nephron, 144(12), 650–654 . https://doi.org/10.1159/000508504

Andersen, M. N., Skovbo, A., Petersen, C. C. & Hokland, M. (2020). Application Settings versus Fixed Photomultiplier Tube Voltages for Optimal Cytometer Stability over Time, and Effect on Reusing a Compensation Matrix. Cytometry. Part A, 97(9), 965-974. https://doi.org/10.1002/cyto.a.24013

Pedersbæk, D., Jønsson, K., Madsen, D. V., Weller, S., Bohn, A. B., Andresen, T. L. & Simonsen, J. B. (2020). A quantitative: Ex vivo study of the interactions between reconstituted high-density lipoproteins and human leukocytes. RSC Advances, 10(7), 3884-3894. https://doi.org/10.1039/c9ra08203d

Cehofski, L. J., Kojima, K., Terao, N., Kitazawa, K., Thineshkumar, S., Grauslund, J., Vorum, H. & Honoré, B. (2020). Aqueous Fibronectin Correlates With Severity of Macular Edema and Visual Acuity in Patients With Branch Retinal Vein Occlusion: A Proteome Study. Investigative Ophthalmology & Visual Science, 61(14), Artikel 6. https://doi.org/10.1167/iovs.61.14.6

Larsen, A. H., Jessen, N., Nørrelund, H., Tolbod, L. P., Harms, H. J., Feddersen, S., Nielsen, F., Brøsen, K., Hansson, N. H., Frøkiaer, J., Poulsen, S. H., Sörensen, J. & Wiggers, H. (2020). A randomised, double-blind, placebo-controlled trial of metformin on myocardial efficiency in insulin-resistant chronic heart failure patients without diabetes. European Journal of Heart Failure, 22(9), 1628-1637. https://doi.org/10.1002/ejhf.1656

Milling, R. V., Niemann, I. C. S., Nielsen Dominiak, H., Hansen, E. S., Sunde, L. & Jensen, J. B. (2020). A rare case of urothelial carcinoma with syncytiotrophoblastic cell differentiation. Scandinavian Journal of Urology, 54(4), 358-359. https://doi.org/10.1080/21681805.2020.1790652

Chen, H., Simonsen, U. & Aalkjaer, C. (2020). A sex-specific, COX-derived/thromboxane-receptor activator causes depolarization and vasoconstriction in male mice mesenteric resistance arteries. Basic and Clinical Pharmacology and Toxicology, 127(2), 152-159. https://doi.org/10.1111/bcpt.13413

Bian, Q., Cheng, Y.-H., Wilson, J. P., Su, E. Y., Kim, D. W., Wang, H., Yoo, S., Blackshaw, S. & Cahan, P. (2020). A single cell transcriptional atlas of early synovial joint development. Development (Cambridge), 147(14), dev185777. Artikel dev185777. https://doi.org/10.1242/dev.185777

The Tabula Muris Consortium (2020). A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Nature, 583(7817), 590-595. https://doi.org/10.1038/s41586-020-2496-1

Mulvany, M. J. & Aalkjær, C. (2020). Assessment of small artery structure and function by micromyography. I D. Rizzoni, A. M. Heagerty & E. Agabiti-Rosei (red.), Microcirculation in Cardiovascular Diseases (s. 15-25). Springer Publishing Company.

Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, M., Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, T., Svenning, J.-C. & Horsdal, H. T. (2020). Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia. Schizophrenia Bulletin, 46(6), 1629-1637. https://doi.org/10.1093/schbul/sbaa058

Rasmussen, L. D., Bøttcher, M., Ivarsen, P., Jørgensen, H. S., Nyegaard, M., Buttenschøn, H., Gustafsen, C., Glerup, S., Bøtker, H. E., Svensson, M. & Winther, S. (2020). Association between circulating proprotein convertase subtilisin/kexin type 9 levels and prognosis in patients with severe chronic kidney disease. Nephrology Dialysis Transplantation, 35(4), 632-639. Artikel gfy257. https://doi.org/10.1093/ndt/gfy257

Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J. C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B. ... McGrath, J. J. (2020). Association between Mental Disorders and Subsequent Medical Conditions. The New England Journal of Medicine, 382(18), 1721-1731. https://doi.org/10.1056/NEJMoa1915784

Holt, C. B., Hoffmann-Petersen, I. T., Hansen, T. K., Parving, H.-H., Thiel, S., Hovind, P., Tarnow, L., Rossing, P. & Østergaard, J. A. (2020). Association between severe diabetic retinopathy and lectin pathway proteins - an 18-year follow-up study with newly diagnosed type 1 diabetes patients. Immunobiology, 225(3), Artikel 151939. https://doi.org/10.1016/j.imbio.2020.151939

Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittomäki, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J. ... Rebbeck, T. R. (2020). Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness. Cancer Research, 80(3), 624-638. https://doi.org/10.1158/0008-5472.CAN-19-1840

Lund, L. C., Reilev, M., Hallas, J., Kristensen, K. B., Thomsen, R. W., Christiansen, C. F., Sørensen, H. T., Johansen, N. B., Brun, N. C., Voldstedlund, M., Støvring, H., Thomsen, M. K., Christensen, S. & Pottegård, A. (2020). Association of Nonsteroidal Anti-inflammatory Drug Use and Adverse Outcomes Among Patients Hospitalized With Influenza. JAMA Network Open, 3(7), Artikel e2013880. https://doi.org/10.1001/jamanetworkopen.2020.13880

Jensen, E. G., Jakobsen, T. S., Thiel, S., Askou, A. L. & Corydon, T. J. (2020). Associations between the Complement System and Choroidal Neovascularization in Wet Age-Related Macular Degeneration. International Journal of Molecular Sciences , 21(24), Artikel 9752. https://doi.org/10.3390/ijms21249752

Sokołowska, A., Świerzko, A. S., Gajek, G., Gołos, A., Michalski, M., Nowicki, M., Szala-Poździej, A., Wolska-Washer, A., Brzezińska, O., Wierzbowska, A., Jamroziak, K., Kowalski, M. L., Thiel, S., Matsushita, M., Jensenius, J. C. & Cedzyński, M. (2020). Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults. Scientific Reports, 10(1), Artikel 10561. https://doi.org/10.1038/s41598-020-67516-2

Świerzko, A. S., Michalski, M., Sokołowska, A., Nowicki, M., Szala-Poździej, A., Eppa, Ł., Mitrus, I., Szmigielska-Kapłon, A., Sobczyk-Kruszelnicka, M., Michalak, K., Gołos, A., Wierzbowska, A., Giebel, S., Jamroziak, K., Kowalski, M. L., Brzezińska, O., Thiel, S., Matsushita, M., Jensenius, J. C. ... Cedzyński, M. (2020). Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations. Frontiers in Immunology, 10, Artikel 3097. https://doi.org/10.3389/fimmu.2019.03097

Chen, C., Sellberg, F., Ahlqvist, V. H., Neovius, M., Christiansen, F. & Berglind, D. (2020). Associations of participation in organized sports and physical activity in preschool children: A cross-sectional study. BMC Pediatrics, 20(1), Artikel 328. https://doi.org/10.1186/s12887-020-02222-6

Broadbent, N., Lumeij, L. B., Corcoles, M., Ayres, A. I., Bin Ibrahim, M. Z., Masatsugu, B., Moreno, A., Carames, J. M., Begg, E., Strickland, L., Mazidzoglou, T., Padanyi, A., Munoz-Lopez, M., Takeuchi, T., Peters, M., Morris, R. G. M. & Tse, D. (2020). A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory. European Journal of Neuroscience, 51(7), 1539-1558. https://doi.org/10.1111/ejn.14681

Eiset, A. H., Aoun, M. P., Haddad, R. S., Naja, W. J., Fuursted, K., Nielsen, H. V., Stensvold, C. R., Nielsen, M. S., Gottlieb, A., Frydenberg, M. & Wejse, C. (2020). Asylum seekers' and Refugees' Changing Health (ARCH) study protocol: an observational study in Lebanon and Denmark to assess health implications of long-distance migration on communicable and non-communicable diseases and mental health. BMJ Open, 10(5), Artikel e034412. https://doi.org/10.1136/bmjopen-2019-034412

Berild, J. D., Winje, B. A., Vestrheim, D. F., Slotved, H. C., Valentiner-Branth, P., Roth, A. & Storsäter, J. (2020). A systematic review of studies published between 2016 and 2019 on the effectiveness and efficacy of pneumococcal vaccination on pneumonia and invasive pneumococcal disease in an elderly population. Pathogens, 9(4), Artikel 259. https://doi.org/10.3390/pathogens9040259

Wesch, N., Kirkin, V. & Rogov, V. V. (2020). Atg8-Family Proteins-Structural Features and Molecular Interactions in Autophagy and Beyond. Cells, 9(9), Artikel 2006. https://doi.org/10.3390/cells9092008

Soler Artigas, M., Sánchez-Mora, C., Rovira, P., Richarte, V., Garcia-Martínez, I., Pagerols, M., Demontis, D., Stringer, S., Vink, J. M., Børglum, A. D., Neale, B. M., Franke, B., Faraone, S. V., Casas, M., Ramos-Quiroga, J. A., Ribasés, M., ADHD Group of the Psychiatric Genomics Consortium, International Cannabis Consortium & International Cannabis Consortium (2020). Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality. Molecular Psychiatry, 25(10), 2493-2503. https://doi.org/10.1038/s41380-018-0339-3

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